SSTR2 Antibody (PACO18928)
- SKU:
- PACO18928
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | SSTR2 Antibody (PACO18928) |
抗体コード: | PACO18928 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human SSTR2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 10%SDS-PAGE, Lysate: 60 μg, Lane: Mouse thymus tissue, Primary antibody: PACO18928(SSTR2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO18928(SSTR2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. |
シノニム: | somatostatin receptor 2 |
UniProt Protein Function: | SSTR2: Receptor for somatostatins-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. In RIN-5F cells, this receptor inhibits calcium entry by suppressing voltage dependent calcium-channels. The C-terminus interacts with SHANK1 PDZ domain. Cerebrum and kidney. In lesser amounts in jejunum, colon and liver. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; GPCR, family 1; Membrane protein, multi-pass; Receptor, GPCR Chromosomal Location of Human Ortholog: 17q24 Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane Molecular Function:neuropeptide binding; protein binding; somatostatin receptor activity; PDZ domain binding Biological Process: peristalsis; regulation of muscle contraction; response to starvation; synaptic transmission; negative regulation of cell proliferation; G-protein signaling, coupled to cyclic nucleotide second messenger; cell-cell signaling; neuropeptide signaling pathway; forebrain development; digestion; cerebellum development; spermatogenesis; G-protein signaling, adenylate cyclase inhibiting pathway; response to nutrient |
NCBI Summary: | Somatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein-coupled receptors that are expressed in a tissue-specific manner. SSTR2 is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney. [provided by RefSeq, Jul 2008] |
UniProt Code: | P30874 |
NCBI GenInfo Identifier: | 401126 |
NCBI Gene ID: | 6752 |
NCBI Accession: | P30874.1 |
UniProt Secondary Accession: | P30874,Q4VBP0, Q96GE0, Q96TF2, Q9BWH1, A8K3Y0, B2R9P7 |
UniProt Related Accession: | P30874 |
Molecular Weight: | 369 |
NCBI Full Name: | Somatostatin receptor type 2 |
NCBI Synonym Full Names: | somatostatin receptor 2 |
NCBI Official Symbol: | SSTR2 |
NCBI Protein Information: | somatostatin receptor type 2; SS2R; SRIF-1 |
UniProt Protein Name: | Somatostatin receptor type 2 |
UniProt Synonym Protein Names: | SRIF-1 |
UniProt Gene Name: | SSTR2 |
UniProt Entry Name: | SSR2_HUMAN |
Antibodies | ELISA Kits |
Anti-SSTR2 Antibody (CAB15101) | Human Somatostatin receptor type 2 / SSTR2 ELISA Kit |
Anti-SSTR2 Antibody (CAB3135) | Human Somatostatin receptor type 2 (SSTR2) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |