SPOPL Antibody, HRP conjugated (PACO57989)
- SKU:
- PACO57989
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SPOPL Antibody, HRP conjugated (PACO57989) |
抗体コード: | PACO57989 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Speckle-type POZ protein-like protein (1-120AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP. |
シノニム: | Speckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2), SPOPL |
UniProt Protein Function: | SPOPL: In complex with a cullin, may act in ubiquitination and proteasomal degradation processes. Belongs to the Tdpoz family.Protein type: Transcription, coactivator/corepressorChromosomal Location of Human Ortholog: 2q22.1Molecular Function: protein bindingBiological Process: negative regulation of protein ubiquitination; proteasomal ubiquitin-dependent protein catabolic process |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q6IQ16 |
NCBI GenInfo Identifier: | 74736582 |
NCBI Gene ID: | 339745 |
NCBI Accession: | Q6IQ16.1 |
UniProt Secondary Accession: | Q6IQ16 |
UniProt Related Accession: | Q6IQ16 |
Molecular Weight: | 44,647 Da |
NCBI Full Name: | Speckle-type POZ protein-like |
NCBI Synonym Full Names: | speckle type BTB/POZ protein like |
NCBI Official Symbol: | SPOPL |
NCBI Official Synonym Symbols: | BTBD33 |
NCBI Protein Information: | speckle-type POZ protein-like |
UniProt Protein Name: | Speckle-type POZ protein-like |
UniProt Synonym Protein Names: | HIB homolog 2; Roadkill homolog 2 |
Protein Family: | Speckle-type POZ protein |
UniProt Gene Name: | SPOPL |
UniProt Entry Name: | SPOPL_HUMAN |