SMNDC1 Antibody (PACO30004)
- SKU:
- PACO30004
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IP
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SMNDC1 Antibody (PACO30004) |
抗体コード: | PACO30004 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IP |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IP:1:200-1:2000 |
反応性: | Human |
免疫原: | Recombinant Human Survival of motor neuron-related-splicing factor 30 protein (1-238AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human heart tissue using PACO30004 at dilution of 1:100. | |
Immunoprecipitating SMNDC1 in Hela whole cell lysate Lane 1: Rabbit control IgG (1µg) instead of PACO30004 in Hela whole cell lysate.For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000) Lane 2: PACO30004 (6µg) + Hela whole cell lysate (500µg) Lane 3: Hela whole cell lysate (10µg) . |
バックグラウンド: | Necessary for spliceosome assembly. Overexpression causes apoptosis. |
シノニム: | Survival of motor neuron-related-splicing factor 30 (30 kDa splicing factor SMNrp) (SMN-related protein) (Survival motor neuron domain-containing protein 1), SMNDC1, SMNR SPF30 |
UniProt Protein Function: | SPF30: Necessary for spliceosome assembly. Overexpression causes apoptosis. Belongs to the SMN family. |
UniProt Protein Details: | Protein type:Spliceosome; RNA processing; RNA splicing; RNA-binding Chromosomal Location of Human Ortholog: 10q23 Cellular Component: nucleoplasm; spliceosome; Cajal body; intermediate filament cytoskeleton; cytoplasm; nuclear speck; nucleus Molecular Function:protein binding Biological Process: RNA splicing, via transesterification reactions; apoptosis; RNA splicing; spliceosome assembly; mRNA processing |
NCBI Summary: | This gene is a paralog of SMN1 gene, which encodes the survival motor neuron protein, mutations in which are cause of autosomal recessive proximal spinal muscular atrophy. The protein encoded by this gene is a nuclear protein that has been identified as a constituent of the spliceosome complex. This gene is differentially expressed, with abundant levels in skeletal muscle, and may share similar cellular function as the SMN1 gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75940 |
NCBI GenInfo Identifier: | 37087924 |
NCBI Gene ID: | 10285 |
NCBI Accession: | O75940.1 |
UniProt Related Accession: | O75940 |
Molecular Weight: | |
NCBI Full Name: | Survival of motor neuron-related-splicing factor 30 |
NCBI Synonym Full Names: | survival motor neuron domain containing 1 |
NCBI Official Symbol: | SMNDC1 |
NCBI Official Synonym Symbols: | SMNR; SPF30; TDRD16C |
NCBI Protein Information: | survival of motor neuron-related-splicing factor 30 |
UniProt Protein Name: | Survival of motor neuron-related-splicing factor 30 |
UniProt Synonym Protein Names: | 30 kDa splicing factor SMNrp; SMN-related protein; Survival motor neuron domain-containing protein 1 |
Protein Family: | Survival of motor neuron-related-splicing factor |
UniProt Gene Name: | SMNDC1 |
UniProt Entry Name: | SPF30_HUMAN |