SLC39A7 Antibody (PACO45628)
- SKU:
- PACO45628
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC39A7 Antibody (PACO45628) |
抗体コード: | PACO45628 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Zinc transporter SLC39A7 protein (235-380AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: SLC39A7 antibody at 3.59µg/ml. Lane 1: MCF-7 whole cell lysate. Lane 2: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51 kDa. Observed band size: 51 kDa.. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45628 at dilution of 1:100. |
バックグラウンド: | Zinc transporter, that transports Zn(2+) from the endoplasmic reticulum/Golgi apparatus to the cytosol. Transport is stimulated by growth factors, such as EGF, and Ca(2+), as well as by exogenous Zn(2+). |
シノニム: | Zinc transporter SLC39A7 (Histidine-rich membrane protein Ke4) (Really interesting new gene 5 protein) (Solute carrier family 39 member 7) (Zrt-, Irt-like protein 7) (ZIP7), SLC39A7, HKE4 RING5 |
UniProt Protein Function: | SLC39A7: transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011] |
UniProt Protein Details: | Protein type:Transporter; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: nucleoplasm; Golgi apparatus; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; integral to membrane Molecular Function:metal ion transmembrane transporter activity; protein binding Biological Process: zinc ion transport; transmembrane transport |
NCBI Summary: | The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
UniProt Code: | Q92504 |
NCBI GenInfo Identifier: | 12643344 |
NCBI Gene ID: | 7922 |
NCBI Accession: | Q92504.2 |
UniProt Secondary Accession: | Q92504,Q5STP8, Q9UIQ0, B0UXF6, |
UniProt Related Accession: | Q92504 |
Molecular Weight: | 469 |
NCBI Full Name: | Zinc transporter SLC39A7 |
NCBI Synonym Full Names: | solute carrier family 39 (zinc transporter), member 7 |
NCBI Official Symbol: | SLC39A7 |
NCBI Official Synonym Symbols: | KE4; HKE4; ZIP7; RING5; H2-KE4; D6S115E; D6S2244E |
NCBI Protein Information: | zinc transporter SLC39A7; zrt-, Irt-like protein 7; Ke4 gene, mouse, human homolog of; solute carrier family 39 member 7; histidine-rich membrane protein Ke4; really interesting new gene 5 protein; HLA class II region expressed gene KE4 |
UniProt Protein Name: | Zinc transporter SLC39A7 |
UniProt Synonym Protein Names: | Histidine-rich membrane protein Ke4; Really interesting new gene 5 protein; Solute carrier family 39 member 7; Zrt-, Irt-like protein 7; ZIP7 |
Protein Family: | Zinc transporter |
UniProt Gene Name: | SLC39A7 |
UniProt Entry Name: | S39A7_HUMAN |