SLC25A5 Antibody, HRP conjugated (PACO46207)
- SKU:
- PACO46207
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | SLC25A5 Antibody, HRP conjugated (PACO46207) |
抗体コード: | PACO46207 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human ADP/ATP translocase 2 protein (144-175AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. |
シノニム: | ADP/ATP translocase 2 (ADP,ATP carrier protein 2) (ADP,ATP carrier protein, fibroblast isoform) (Adenine nucleotide translocator 2) (ANT 2) (Solute carrier family 25 member 5) [Cleaved into: ADP/ATP translocase 2, N-terminally processed], SLC25A5, ANT2 |
UniProt Protein Function: | SLC25A5: Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation. Belongs to the mitochondrial carrier family. |
UniProt Protein Details: | Protein type:Transporter; Mitochondrial; Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: Xq24 Cellular Component: integral to plasma membrane; membrane; mitochondrial inner membrane; mitochondrion; myelin sheath; nucleus Molecular Function:adenine transmembrane transporter activity; protein binding; structural constituent of ribosome; ubiquitin protein ligase binding Biological Process: adenine transport; chromosome segregation; positive regulation of cell proliferation; regulation of insulin secretion; translation; transmembrane transport; transport; viral reproduction |
NCBI Summary: | This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013] |
UniProt Code: | P05141 |
NCBI GenInfo Identifier: | 317373597 |
NCBI Gene ID: | 292 |
NCBI Accession: | P05141.7 |
UniProt Secondary Accession: | P05141,O43350, B2RCV1, |
UniProt Related Accession: | P05141 |
Molecular Weight: | 33-36 kDa |
NCBI Full Name: | ADP/ATP translocase 2 |
NCBI Synonym Full Names: | solute carrier family 25 member 5 |
NCBI Official Symbol: | SLC25A5 |
NCBI Official Synonym Symbols: | T2; T3; 2F1; AAC2; ANT2 |
NCBI Protein Information: | ADP/ATP translocase 2 |
UniProt Protein Name: | ADP/ATP translocase 2 |
UniProt Synonym Protein Names: | ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; Adenine nucleotide translocator 2; ANT 2 |
Protein Family: | ADP/ATP translocase |
UniProt Gene Name: | SLC25A5 |
UniProt Entry Name: | ADT2_HUMAN |