SLC1A6 Antibody (PACO17810)
- SKU:
- PACO17810
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC1A6 Antibody (PACO17810) |
抗体コード: | PACO17810 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:500-1:5000, WB:1:500-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human SLC1A6 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO17810(SLC1A6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 10%SDS-PAGE, Lysate: 30 μg, Lane: Mouse brain tissue, Primary antibody: PACO17810(SLC1A6 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO17810(SLC1A6 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Excitatory amino-acid, transporter 4 (EAAT4) is a protein that in humans is encoded by the SLC1A6 gene.It is a member of the high-affinity glutamate and neutral amino acid, transporter family. It transports L-glutamate and also L- and D-aspartate predominantly in the cerebellar cortex. Genetic polymorphism in the SLC1A6 gene is suggested to be refered to glutamatergic dysfunction in schizophrenia pathogenesis. |
シノニム: | Solute carrier family 1 member 6 |
UniProt Protein Function: | SLC1A6: Transports L-glutamate and also L- and D-aspartate. Seems to act as a symport by cotransporting sodium. Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family. SLC1A6 subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Transporter; Transporter, SLC family; Membrane protein, integral Chromosomal Location of Human Ortholog: 19p13.12 Cellular Component: Golgi apparatus; membrane; integral to plasma membrane; plasma membrane Molecular Function:L-aspartate transmembrane transporter activity; sodium:dicarboxylate symporter activity; L-glutamate transmembrane transporter activity Biological Process: synaptic transmission; regulation of membrane potential; L-glutamate transport; ion transport; aspartate transport; transmembrane transport |
UniProt Code: | P48664 |
NCBI GenInfo Identifier: | 1352333 |
NCBI Gene ID: | 6511 |
NCBI Accession: | P48664.1 |
UniProt Secondary Accession: | P48664,Q8N753, |
UniProt Related Accession: | P48664 |
Molecular Weight: | 564 |
NCBI Full Name: | Excitatory amino acid transporter 4 |
NCBI Synonym Full Names: | solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6 |
NCBI Official Symbol: | SLC1A6 |
NCBI Official Synonym Symbols: | EAAT4 |
NCBI Protein Information: | excitatory amino acid transporter 4; solute carrier family 1 member 6; sodium-dependent glutamate/aspartate transporter |
UniProt Protein Name: | Excitatory amino acid transporter 4 |
UniProt Synonym Protein Names: | Sodium-dependent glutamate/aspartate transporter; Solute carrier family 1 member 6 |
Protein Family: | Excitatory amino acid transporter |
UniProt Gene Name: | SLC1A6 |
UniProt Entry Name: | EAA4_HUMAN |