SLC14A1 Antibody (PACO57112)
- SKU:
- PACO57112
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SLC14A1 Antibody (PACO57112) |
抗体コード: | PACO57112 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Urea transporter 1 protein (1-51AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO57112 diluted at 1:200 and staining in paraffin-embedded human prostate tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
Immunofluorescence staining of MCF-7 cells with PACO57112 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
IHC image of PACO57112 diluted at 1:200 and staining in paraffin-embedded human prostate cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Urea channel that facilitates transmembrane urea transport down a concentration gradient. A constriction of the transmembrane channel functions as selectivity filter through which urea is expected to pass in dehydrated form. The rate of urea conduction is increased by hypotonic stress. Plays an important role in the kidney medulla collecting ducts, where it allows rapid equilibration between the lumen of the collecting ducts and the interstitium, and thereby prevents water loss driven by the high concentration of urea in the urine. Facilitates urea transport across erythrocyte membranes. May also play a role in transmembrane water transport, possibly by indirect means. |
シノニム: | Urea transporter 1 (Solute carrier family 14 member 1) (Urea transporter, erythrocyte), SLC14A1, HUT11 JK RACH1 UT1 UTE |
NCBI Summary: | The protein encoded by this gene is a membrane transporter that mediates urea transport in erythrocytes. This gene forms the basis for the Kidd blood group system. [provided by RefSeq, Mar 2009] |
UniProt Code: | Q13336 |
NCBI GenInfo Identifier: | 226371768 |
NCBI Gene ID: | 6563 |
NCBI Accession: | NP_001122060.3 |
UniProt Related Accession: | Q13336 |
Molecular Weight: | |
NCBI Full Name: | urea transporter 1 isoform 1 |
NCBI Synonym Full Names: | solute carrier family 14 member 1 (Kidd blood group) |
NCBI Official Symbol: | SLC14A1 |
NCBI Official Synonym Symbols: | JK; UT1; UTE; HUT11; RACH1; RACH2; UT-B1; HsT1341 |
NCBI Protein Information: | urea transporter 1 |
UniProt Protein Name: | Urea transporter 1 |
UniProt Synonym Protein Names: | Solute carrier family 14 member 1; Urea transporter, erythrocyte |
UniProt Gene Name: | SLC14A1 |
UniProt Entry Name: | UT1_HUMAN |
Antibodies | ELISA Kits |
Anti-SLC14A1 Antibody (CAB15991) | Human SLC14A1 / Urea transporter 1 ELISA Kit |
Human Urea transporter 1 (SLC14A1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |