SIGLEC6 Antibody (PACO19418)
- SKU:
- PACO19418
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SIGLEC6 Antibody (PACO19418) |
抗体コード: | PACO19418 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Synthetic peptide of human SIGLEC6 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO19418(SIGLEC6 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Human placenta tissue, Primary antibody: PACO19418(SIGLEC6 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19418(SIGLEC6 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The SIGLEC6 gene to 19q13.3, which is where the CD33 gene is located. Putative adhesion molecule that mediates sialic-acid, dependent binding to cells. Binds to alpha-2,6-linked sialic acid, The sialic acid, recognition site may be masked by cis interactions with sialic acid, on the same cell surface. Expressed at high levels in placenta (cyto- and syncytiotrophoblastic cells) and at lower levels in spleen, peripheral blood leukocytes (predominantly B-cells) and small intestine. |
シノニム: | sialic acid, binding Ig-like lectin 6 |
UniProt Protein Function: | Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
NCBI Summary: | This gene encodes a member of the SIGLEC (sialic acid binding immunoglobulin-like lectin) family of proteins. The encoded transmembrane receptor binds sialyl-TN glycans and leptin. Placental expression of the encoded protein is upregulated in preeclampsia. [provided by RefSeq, Jul 2016] |
UniProt Code: | O43699 |
NCBI GenInfo Identifier: | 215273884 |
NCBI Gene ID: | 946 |
NCBI Accession: | O43699.2 |
UniProt Secondary Accession: | O43699,O15388, O43700, A8MV71, B2RTS8, C9JBE5, F8WA78 |
UniProt Related Accession: | O43699 |
Molecular Weight: | 44,348 Da |
NCBI Full Name: | Sialic acid-binding Ig-like lectin 6 |
NCBI Synonym Full Names: | sialic acid binding Ig like lectin 6 |
NCBI Official Symbol: | SIGLEC6 |
NCBI Official Synonym Symbols: | CD327; CD33L; OBBP1; CD33L1; CD33L2; CDW327 |
NCBI Protein Information: | sialic acid-binding Ig-like lectin 6 |
UniProt Protein Name: | Sialic acid-binding Ig-like lectin 6 |
UniProt Synonym Protein Names: | CD33 antigen-like 1; CDw327; Obesity-binding protein 1; OB-BP1; CD_antigen: CD327 |
Protein Family: | Sialic acid-binding Ig-like lectin |
UniProt Gene Name: | SIGLEC6 |