SGPL1 Antibody (PACO20452)
- SKU:
- PACO20452
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SGPL1 Antibody (PACO20452) |
抗体コード: | PACO20452 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human SGPL1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20452(SGPL1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE,Lysate: 40 μgPrimary antibody: PACO20452(SGPL1 Antibody) at dilution 1/200 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 second. | |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20452(SGPL1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Sphingosine-1-phosphate lyase 1 is an enzyme that in humans is encoded by the SGPL1gene. Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. |
シノニム: | sphingosine-1-phosphate lyase 1 |
UniProt Protein Function: | SGPL1: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. Belongs to the group II decarboxylase family. Sphingosine-1-phosphate lyase subfamily. |
UniProt Protein Details: | Protein type:Apoptosis; Lipid Metabolism - sphingolipid; EC 4.1.2.27; Lyase; Membrane protein, integral Chromosomal Location of Human Ortholog: 10q21 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane Molecular Function:protein binding; sphinganine-1-phosphate aldolase activity Biological Process: ceramide metabolic process; fatty acid metabolic process; sphingolipid biosynthetic process; sphingolipid catabolic process |
UniProt Code: | O95470 |
NCBI GenInfo Identifier: | 37999486 |
NCBI Gene ID: | 8879 |
NCBI Accession: | O95470.3 |
UniProt Secondary Accession: | O95470,Q7Z732, Q9ULG8, Q9UN89, B2RBD4, |
UniProt Related Accession: | O95470 |
Molecular Weight: | 63,524 Da |
NCBI Full Name: | Sphingosine-1-phosphate lyase 1 |
NCBI Synonym Full Names: | sphingosine-1-phosphate lyase 1 |
NCBI Official Symbol: | SGPL1 |
NCBI Official Synonym Symbols: | SPL; S1PL |
NCBI Protein Information: | sphingosine-1-phosphate lyase 1 |
UniProt Protein Name: | Sphingosine-1-phosphate lyase 1 |
UniProt Synonym Protein Names: | Sphingosine-1-phosphate aldolase |
Protein Family: | Sphingosine-1-phosphate lyase |
UniProt Gene Name: | SGPL1 |
UniProt Entry Name: | SGPL1_HUMAN |
Antibodies | ELISA Kits |
Anti-SGPL1 Antibody (CAB15745) | Human Sphingosine-1-phosphate lyase 1 (SGPL1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |