SERPINB2 Antibody (PACO16833)
- SKU:
- PACO16833
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SERPINB2 Antibody (PACO16833) |
抗体コード: | PACO16833 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human SERPINB2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16833(SERPINB2 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Plasminogen activator inhibitor-2 (placental PAI) is a coagulation factor that inactivates tPA and urokinase. It is present in most cells, especiallymonocytes/macrophages. PAI-2 exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosis during pregnancy. |
シノニム: | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
UniProt Protein Function: | SERPINB2: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. Belongs to the serpin family. Ov-serpin subfamily. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 18q21.3 Cellular Component: extracellular space; cytoplasm; plasma membrane; extracellular region Molecular Function:serine-type endopeptidase inhibitor activity Biological Process: fibrinolysis; blood coagulation; negative regulation of apoptosis |
UniProt Code: | P05120 |
NCBI GenInfo Identifier: | 1352712 |
NCBI Gene ID: | 5055 |
NCBI Accession: | P05120.2 |
UniProt Secondary Accession: | P05120,Q96E96, |
UniProt Related Accession: | P05120 |
Molecular Weight: | 46,596 Da |
NCBI Full Name: | Plasminogen activator inhibitor 2 |
NCBI Synonym Full Names: | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
NCBI Official Symbol: | SERPINB2 |
NCBI Official Synonym Symbols: | PAI; PAI2; PAI-2; PLANH2; HsT1201 |
NCBI Protein Information: | plasminogen activator inhibitor 2; serpin B2; monocyte Arg-serpin; urokinase inhibitor; placental plasminogen activator inhibitor; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2 |
UniProt Protein Name: | Plasminogen activator inhibitor 2 |
UniProt Synonym Protein Names: | Monocyte Arg-serpin; Placental plasminogen activator inhibitor; Serpin B2; Urokinase inhibitor |
UniProt Gene Name: | SERPINB2 |
UniProt Entry Name: | PAI2_HUMAN |
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