SEPT2 Antibody (PACO17074)
- SKU:
- PACO17074
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SEPT2 Antibody (PACO17074) |
抗体コード: | PACO17074 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Full length fusion protein |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: PACO17074(SEPT2 Antibody) at dilution 1/400 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 10S. | |
The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using PACO17074(SEPT2 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. |
シノニム: | septin 2 |
UniProt Protein Function: | SEPT2: a member of the septin family of proteins. May be involved in the process of cytokinesis. Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localized to fibrous or granular structures, depending on the growth state of the cell. |
UniProt Protein Details: | Protein type:Cytoskeletal; Hydrolase; Cell development/differentiation; Motility/polarity/chemotaxis; Cell cycle regulation Chromosomal Location of Human Ortholog: 2q37 Cellular Component: nucleoplasm; perinuclear region of cytoplasm; cytoplasm; nucleolus; exocyst; synapse; spindle; midbody; cell cortex; nucleus; actin cytoskeleton; cleavage furrow Molecular Function:protein binding; GTP binding; protein complex scaffold; enzyme regulator activity Biological Process: mitosis; smoothened signaling pathway; regulation of protein localization; regulation of catalytic activity; cell division; cilium biogenesis; regulation of L-glutamate transport; neurite development |
UniProt Code: | Q15019 |
NCBI GenInfo Identifier: | 2500769 |
NCBI Gene ID: | 4735 |
NCBI Accession: | Q15019.1 |
UniProt Secondary Accession: | Q15019,Q14132, Q53QU3, Q8IUK9, Q96CB0, B4DGE8, |
UniProt Related Accession: | Q15019 |
Molecular Weight: | 361 |
NCBI Full Name: | Septin-2 |
NCBI Synonym Full Names: | septin 2 |
NCBI Official Symbol: | SEPT2 |
NCBI Official Synonym Symbols: | DIFF6; NEDD5; NEDD-5; Pnutl3; hNedd5 |
NCBI Protein Information: | septin-2; neural precursor cell expressed, developmentally down-regulated 5; neural precursor cell expressed developmentally down-regulated protein 5 |
UniProt Protein Name: | Septin-2 |
UniProt Synonym Protein Names: | Neural precursor cell expressed developmentally down-regulated protein 5; NEDD-5 |
UniProt Gene Name: | SEPT2 |
UniProt Entry Name: | SEPT2_HUMAN |