SEPP1 Antibody (PACO17060)
- SKU:
- PACO17060
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SEPP1 Antibody (PACO17060) |
抗体コード: | PACO17060 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Fusion protein of human SEPP1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO17060(SEPP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO17060(SEPP1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene. |
シノニム: | selenoprotein P, plasma, 1 |
UniProt Protein Function: | SEPP1: Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis. Belongs to the selenoprotein P family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 5q31 Cellular Component: extracellular region Biological Process: platelet degranulation; response to oxidative stress |
NCBI Summary: | This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P49908 |
NCBI GenInfo Identifier: | 172046864 |
NCBI Gene ID: | 6414 |
NCBI Accession: | P49908.3 |
UniProt Secondary Accession: | P49908,Q6PD59, Q6PI43, Q6PI87, Q6PJF9, |
UniProt Related Accession: | P49908 |
Molecular Weight: | 43,174 Da |
NCBI Full Name: | Selenoprotein P |
NCBI Synonym Full Names: | selenoprotein P, plasma, 1 |
NCBI Official Symbol: | SEPP1 |
NCBI Official Synonym Symbols: | SeP; SELP; SEPP |
NCBI Protein Information: | selenoprotein P |
UniProt Protein Name: | Selenoprotein P |
Protein Family: | Selenoprotein |
UniProt Gene Name: | SEPP1 |
UniProt Entry Name: | SEPP1_HUMAN |
ELISA Kits |
Human SEPP1 (Selenoprotein P) ELISA Kit |
Human SEPP1 (Selenoprotein P, Plasma) CLIA Kit (HUES01150) |
Human Selenoprotein P (SEPP1) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |