SEC23B Antibody (PACO59077)
- SKU:
- PACO59077
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | SEC23B Antibody (PACO59077) |
抗体コード: | PACO59077 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Protein transport protein Sec23B protein (208-325AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO59077 diluted at 1:300 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. | |
IHC image of PACO59077 diluted at 1:300 and staining in paraffin-embedded human appendix tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex (By similarity). |
シノニム: | Protein transport protein Sec23B (hSec23B) (SEC23-related protein B), SEC23B |
UniProt Protein Function: | SEC23B: Component of the COPII coat, that covers ER-derived vesicles involved in transport from the endoplasmic reticulum to the Golgi apparatus. COPII acts in the cytoplasm to promote the transport of secretory, plasma membrane, and vacuolar proteins from the endoplasmic reticulum to the Golgi complex. COPII is composed of at least five proteins: the Sec23/24 complex, the Sec13/31 complex and Sar1. Belongs to the SEC23/SEC24 family. SEC23 subfamily. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 20p11.23 Cellular Component: endomembrane system; intracellular membrane-bound organelle; membrane Molecular Function:protein binding Biological Process: vesicle-mediated transport Disease: Anemia, Congenital Dyserythropoietic, Type Ii |
NCBI Summary: | The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The function of this gene product has been implicated in cargo selection and concentration. Multiple alternatively spliced transcript variants have been identified in this gene. [provided by RefSeq, Feb 2010] |
UniProt Code: | Q15437 |
NCBI GenInfo Identifier: | 20141794 |
NCBI Gene ID: | 10483 |
NCBI Accession: | Q15437.2 |
UniProt Secondary Accession: | Q15437,Q503A9, Q5W183, Q9BS15, Q9BSI2, Q9H1D7, D3DW33 |
UniProt Related Accession: | Q15437 |
Molecular Weight: | 86,479 Da |
NCBI Full Name: | Protein transport protein Sec23B |
NCBI Synonym Full Names: | Sec23 homolog B, coat complex II component |
NCBI Official Symbol: | SEC23B |
NCBI Official Synonym Symbols: | CWS7; CDAII; CDAN2; CDA-II; HEMPAS |
NCBI Protein Information: | protein transport protein Sec23B |
UniProt Protein Name: | Protein transport protein Sec23B |
UniProt Synonym Protein Names: | SEC23-related protein B |
Protein Family: | Protein transport protein |
UniProt Gene Name: | SEC23B |
UniProt Entry Name: | SC23B_HUMAN |