S1PR2 Antibody (PACO05738)
- SKU:
- PACO05738
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | S1PR2 Antibody (PACO05738) |
抗体コード: | PACO05738 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the C-terminal region of human EDG-5. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | S1PR2; EDG5; Sphingosine 1-phosphate receptor 2; S1P receptor 2; S1P2; Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5 |
UniProt Protein Function: | EDG5: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Membrane protein, multi-pass; GPCR, family 1; Receptor, GPCR; Membrane protein, integral; Lipid-binding Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: integral to membrane; plasma membrane Molecular Function:G-protein coupled receptor activity; G-protein-coupled receptor binding; integrin binding; lipid binding; protein binding Biological Process: actin cytoskeleton reorganization; activation of MAPK activity; filopodium formation; G-protein coupled receptor protein signaling pathway; positive regulation of cell proliferation |
NCBI Summary: | This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016] |
UniProt Code: | O95136 |
NCBI GenInfo Identifier: | 38257367 |
NCBI Gene ID: | 9294 |
NCBI Accession: | O95136.2 |
UniProt Secondary Accession: | O95136,Q86UN8, |
UniProt Related Accession: | O95136 |
Molecular Weight: | 38,867 Da |
NCBI Full Name: | Sphingosine 1-phosphate receptor 2 |
NCBI Synonym Full Names: | sphingosine-1-phosphate receptor 2 |
NCBI Official Symbol: | S1PR2 |
NCBI Official Synonym Symbols: | EDG5; H218; LPB2; S1P2; AGR16; EDG-5; DFNB68; Gpcr13 |
NCBI Protein Information: | sphingosine 1-phosphate receptor 2 |
UniProt Protein Name: | Sphingosine 1-phosphate receptor 2 |
UniProt Synonym Protein Names: | Endothelial differentiation G-protein coupled receptor 5; Sphingosine 1-phosphate receptor Edg-5; S1P receptor Edg-5 |
Protein Family: | Sphingosine 1-phosphate receptor |
UniProt Gene Name: | S1PR2 |
UniProt Entry Name: | S1PR2_HUMAN |