S100A11 Antibody (PACO04981)
- SKU:
- PACO04981
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | S100A11 Antibody |
抗体コード: | PACO04981 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the Internal region of human Calgizzarin. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | S100A11; MLN70; S100C; Protein S100-A11; Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70; Protein S100-C; S100 calcium-binding protein A11 |
UniProt Protein Function: | S100A11: a calcium-binding regulatory protein of the S-100 family. Interacts with the N-termini of annexins A1. May regulate fusion processes such as endo- and exocytosis. Increases in the early stage of pancreatic carcinogenesis and decreases during subsequent progression to cancer. Increased expression in anaplastic large cell lymphoma. |
UniProt Protein Details: | Protein type:Calcium-binding; DNA replication; Cell cycle regulation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: cytoplasm; extracellular space; nucleus; ruffle Molecular Function:calcium-dependent protein binding; protein binding; protein homodimerization activity Biological Process: negative regulation of cell proliferation; negative regulation of DNA replication; signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of this gene have been implicated in tumor metastasis. [provided by RefSeq, Jul 2008] |
UniProt Code: | P31949 |
NCBI GenInfo Identifier: | 1710818 |
NCBI Gene ID: | 6282 |
NCBI Accession: | P31949.2 |
UniProt Secondary Accession: | P31949,Q5VTK0, |
UniProt Related Accession: | P31949 |
Molecular Weight: | 11,740 Da |
NCBI Full Name: | Protein S100-A11 |
NCBI Synonym Full Names: | S100 calcium binding protein A11 |
NCBI Official Symbol: | S100A11 |
NCBI Official Synonym Symbols: | MLN70; S100C; HEL-S-43 |
NCBI Protein Information: | protein S100-A11 |
UniProt Protein Name: | Protein S100-A11 |
UniProt Synonym Protein Names: | Calgizzarin; Metastatic lymph node gene 70 protein; MLN 70 |
Protein Family: | Protein |
UniProt Gene Name: | S100A11 |
UniProt Entry Name: | S10AB_HUMAN |