RPUSD4 Antibody (PACO38430)
- SKU:
- PACO38430
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RPUSD4 Antibody (PACO38430) |
抗体コード: | PACO38430 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Mitochondrial RNA pseudouridine synthase RPUSD4 protein (41-240AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: RPUSD4 antibody at 0.5µg/ml + MCF-7 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43, 39 kDa. Observed band size: 43 kDa. | |
Immunohistochemistry of paraffin-embedded human kidney tissue using PACO38430 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO38430 at dilution of 1:100. |
バックグラウンド: | Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt-rRNA, controls 16S mt-rRNA abundance and is required for intra-mitochondrial translation. |
シノニム: | Mitochondrial RNA pseudouridine synthase RPUSD4 (EC 5.4.99.-) (RNA pseudouridylate synthase domain-containing protein 4), RPUSD4 |
UniProt Protein Function: | RPUSD4: Belongs to the pseudouridine synthase RluA family. |
UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 11q24.2 Cellular Component: mitochondrion Molecular Function:deaminase activity; protein binding; pseudouridine synthase activity Biological Process: tRNA pseudouridine synthesis |
UniProt Code: | Q96CM3 |
NCBI GenInfo Identifier: | 221316667 |
NCBI Gene ID: | 84881 |
NCBI Accession: | NP_001138299.1 |
UniProt Secondary Accession: | Q96CM3,Q96K56, E9PML2, |
UniProt Related Accession: | Q96CM3 |
Molecular Weight: | 38,552 Da |
NCBI Full Name: | RNA pseudouridylate synthase domain-containing protein 4 isoform b |
NCBI Synonym Full Names: | RNA pseudouridylate synthase domain containing 4 |
NCBI Official Symbol: | RPUSD4 |
NCBI Protein Information: | RNA pseudouridylate synthase domain-containing protein 4 |
UniProt Protein Name: | RNA pseudouridylate synthase domain-containing protein 4 |
Protein Family: | RNA pseudouridylate synthase domain-containing protein |
UniProt Gene Name: | RPUSD4 |
UniProt Entry Name: | RUSD4_HUMAN |
Antibodies |
Anti-RPUSD4 Antibody (CAB15538) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-HRP-conjugated Beta Actin Antibody (CABC028) |