RPN1 Antibody (PACO31912)
- SKU:
- PACO31912
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RPN1 Antibody (PACO31912) |
抗体コード: | PACO31912 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit protein (44-427AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot All lanes: RPN1 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 50 kDa Observed band size: 50 kDa . | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO31912 at dilution of 1:100. |
シノニム: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit) (Ribophorin I) (RPN-I) (Ribophorin-1), RPN1 |
UniProt Protein Function: | RPN1: Essential subunit of N-oligosaccharyl transferase enzyme which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Belongs to the OST1 family. |
UniProt Protein Details: | Protein type:EC 2.4.99.18; Glycan Metabolism - N-glycan biosynthesis; Transferase; Membrane protein, integral Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: endoplasmic reticulum membrane; membrane; rough endoplasmic reticulum; oligosaccharyl transferase complex; integral to membrane; melanosome Molecular Function:protein binding; dolichyl-diphosphooligosaccharide-protein glycotransferase activity Biological Process: SRP-dependent cotranslational protein targeting to membrane; cellular protein metabolic process; translation; protein modification process; protein amino acid N-linked glycosylation via asparagine; gene expression; post-translational protein modification |
NCBI Summary: | This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P04843 |
NCBI GenInfo Identifier: | 132559 |
NCBI Gene ID: | 6184 |
NCBI Accession: | P04843.1 |
UniProt Secondary Accession: | P04843,Q68DT1, B2R5Z0, D3DNB6, |
UniProt Related Accession: | P04843 |
Molecular Weight: | 607 |
NCBI Full Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
NCBI Synonym Full Names: | ribophorin I |
NCBI Official Symbol: | RPN1 |
NCBI Official Synonym Symbols: | OST1; RBPH1 |
NCBI Protein Information: | dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; RPN-I; ribophorin-1; oligosaccharyltransferase 1 homolog; oligosaccharyltransferase complex subunit (non-catalytic); dolichyl-diphosphooligosaccharide-protein glycosyltransferase 67 kDa subunit; dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit |
UniProt Protein Name: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 |
UniProt Synonym Protein Names: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Ribophorin I; RPN-I; Ribophorin-1 |
Protein Family: | 26S proteasome regulatory |
UniProt Gene Name: | RPN1 |
UniProt Entry Name: | RPN1_HUMAN |