RPLP1 Antibody (PACO17017)
- SKU:
- PACO17017
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RPLP1 Antibody (PACO17017) |
抗体コード: | PACO17017 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human RPLP1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: K562 cells, hepg2 cells, Primary antibody: PACO17017(RPLP1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes. | |
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using PACO17017(RPLP1 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acid, c. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. |
シノニム: | ribosomal protein, large, P1 |
UniProt Protein Function: | RPLP1: Plays an important role in the elongation step of protein synthesis. Belongs to the ribosomal protein L12P family. |
UniProt Protein Details: | Protein type:Translation; Ribosomal Chromosomal Location of Human Ortholog: 15q22 Cellular Component: cytoplasm; cytosol; focal adhesion Molecular Function:protein binding; protein kinase activator activity; structural constituent of ribosome Biological Process: mRNA catabolic process, nonsense-mediated decay; positive regulation of protein kinase activity; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translational initiation; viral transcription |
NCBI Summary: | Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P2. The P1 protein can interact with P0 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Two alternatively spliced transcript variants that encode different proteins have been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P05386 |
NCBI GenInfo Identifier: | 133051 |
NCBI Gene ID: | 6176 |
NCBI Accession: | P05386.1 |
UniProt Secondary Accession: | P05386,A6NIB2, |
UniProt Related Accession: | P05386 |
Molecular Weight: | 8,804 Da |
NCBI Full Name: | 60S acidic ribosomal protein P1 |
NCBI Synonym Full Names: | ribosomal protein lateral stalk subunit P1 |
NCBI Official Symbol: | RPLP1 |
NCBI Official Synonym Symbols: | P1; LP1; RPP1 |
NCBI Protein Information: | 60S acidic ribosomal protein P1 |
UniProt Protein Name: | 60S acidic ribosomal protein P1 |
UniProt Gene Name: | RPLP1 |
UniProt Entry Name: | RLA1_HUMAN |
Antibodies |
Anti-RPLP1 Antibody (CAB6725) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |