RNF125 Antibody (PACO04664)
- SKU:
- PACO04664
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RNF125 Antibody |
抗体コード: | PACO04664 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the Internal region of human TRAC-1. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | RNF125; E3 ubiquitin-protein ligase RNF125; RING finger protein 125; T-cell RING activation protein 1; TRAC-1 |
UniProt Protein Function: | RNF125: E3 ubiquitin-protein ligase that acts as a positive regulator of T-cell activation. E3 ligase proteins mediate ubiquitination and subsequent proteasomal degradation of target proteins. |
UniProt Protein Details: | Protein type:Ubiquitin conjugating system; Ubiquitin ligase; EC 6.3.2.19; EC 6.3.2.-; Ligase Chromosomal Location of Human Ortholog: 18q12.1 Molecular Function:zinc ion binding; ubiquitin-protein ligase activity; ligase activity Biological Process: protein ubiquitination; innate immune response; negative regulation of interferon type I production Disease: Tenorio Syndrome |
NCBI Summary: | This gene encodes a novel E3 ubiquitin ligase that contains a RING finger domain in the N-terminus and three zinc-binding and one ubiquitin-interacting motif in the C-terminus. As a result of myristoylation, this protein associates with membranes and is primarily localized to intracellular membrane systems. The encoded protein may function as a positive regulator in the T-cell receptor signaling pathway. [provided by RefSeq, Mar 2012] |
UniProt Code: | Q96EQ8 |
NCBI GenInfo Identifier: | 37595555 |
NCBI Gene ID: | 54941 |
NCBI Accession: | NP_060301 |
UniProt Related Accession: | Q96EQ8 |
Molecular Weight: | 26kDa |
NCBI Full Name: | E3 ubiquitin-protein ligase RNF125 |
NCBI Synonym Full Names: | ring finger protein 125 |
NCBI Official Symbol: | RNF125 |
NCBI Official Synonym Symbols: | TNORS; TRAC1; TRAC-1 |
NCBI Protein Information: | E3 ubiquitin-protein ligase RNF125 |
UniProt Protein Name: | E3 ubiquitin-protein ligase RNF125 |
UniProt Synonym Protein Names: | RING finger protein 125; T-cell RING activation protein 1 |
Protein Family: | E3 ubiquitin-protein ligase |
UniProt Gene Name: | RNF125 |
UniProt Entry Name: | RN125_HUMAN |