RIOX2 Antibody, HRP conjugated (PACO37659)
- SKU:
- PACO37659
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | RIOX2 Antibody, HRP conjugated (PACO37659) |
抗体コード: | PACO37659 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ribosomal oxygenase 2 protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. |
シノニム: | Ribosomal oxygenase 2 (60S ribosomal protein L27a histidine hydroxylase) (Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA) (EC 1.14.11.-) (Histone lysine demethylase MINA) (MYC-induced nuclear antigen) (Mineral dust-induced gene protein) (Nucleolar protein 52) (Ribosomal oxygenase MINA) (ROX), RIOX2, MDIG MINA MINA53 NO52 |
UniProt Protein Function: | MINA: Involved in cellular proliferation. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles. Belongs to the MINA53/NO66 family. 4 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Nucleolus Chromosomal Location of Human Ortholog: 3q11.2 Cellular Component: transcription factor complex; cytoplasm; nucleolus; cytosol; nucleus Molecular Function:dioxygenase activity; metal ion binding Biological Process: transcription, DNA-dependent; ribosome biogenesis and assembly; negative regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | MINA is a c-Myc (MYC; MIM 190080) target gene that may play a role in cell proliferation or regulation of cell growth. (Tsuneoka et al., 2002 [PubMed 12091391]; Zhang et al., 2005 [PubMed 15897898]).[supplied by OMIM, May 2008] |
UniProt Code: | Q8IUF8 |
NCBI GenInfo Identifier: | 74750624 |
NCBI Gene ID: | 84864 |
NCBI Accession: | Q8IUF8.1 |
UniProt Related Accession: | Q8IUF8 |
Molecular Weight: | |
NCBI Full Name: | Ribosomal oxygenase 2 |
NCBI Synonym Full Names: | ribosomal oxygenase 2 |
NCBI Official Symbol: | RIOX2 |
NCBI Official Synonym Symbols: | ROX; MDIG; MINA; NO52; JMJD10; MINA53 |
NCBI Protein Information: | ribosomal oxygenase 2 |
UniProt Protein Name: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase MINA |
UniProt Synonym Protein Names: | 60S ribosomal protein L27a histidine hydroxylase; Histone lysine demethylase MINA; MYC-induced nuclear antigen; Mineral dust-induced gene protein; Nucleolar protein 52; Ribosomal oxygenase MINA; ROX |
Protein Family: | Bifunctional lysine-specific demethylase and histidyl-hydroxylase |
UniProt Gene Name: | MINA |
UniProt Entry Name: | MINA_HUMAN |