RBMS1 Antibody (PACO55750)
- SKU:
- PACO55750
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | RBMS1 Antibody (PACO55750) |
抗体コード: | PACO55750 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human RNA-binding motif, single-stranded-interacting protein 1 protein (206-277AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: NIH/3T3 whole cell lysate. All lanes: RBMS1 antibody at 3.6µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 45, 5 kDa. Observed band size: 45 kDa. | |
Immunofluorescence staining of HepG2 cells with PACO55750 at 1:120, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. |
シノニム: | RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2), RBMS1, C2orf12 MSSP MSSP1 SCR2 |
UniProt Protein Function: | RBMS1: Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA replication; RNA-binding Chromosomal Location of Human Ortholog: 2q24.2 Cellular Component: nucleus Molecular Function:protein binding; RNA binding; double-stranded DNA binding; nucleotide binding; single-stranded DNA binding Biological Process: RNA processing; DNA replication |
NCBI Summary: | This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009] |
UniProt Code: | P29558 |
NCBI GenInfo Identifier: | 55977783 |
NCBI Gene ID: | 5937 |
NCBI Accession: | P29558.3 |
UniProt Related Accession: | P29558 |
Molecular Weight: | |
NCBI Full Name: | RNA-binding motif, single-stranded-interacting protein 1 |
NCBI Synonym Full Names: | RNA binding motif single stranded interacting protein 1 |
NCBI Official Symbol: | RBMS1 |
NCBI Official Synonym Symbols: | YC1; MSSP; SCR2; HCC-4; MSSP-1; MSSP-2; MSSP-3; C2orf12 |
NCBI Protein Information: | RNA-binding motif, single-stranded-interacting protein 1 |
UniProt Protein Name: | RNA-binding motif, single-stranded-interacting protein 1 |
UniProt Synonym Protein Names: | Single-stranded DNA-binding protein MSSP-1; Suppressor of CDC2 with RNA-binding motif 2 |
Protein Family: | RNA-binding motif, single-stranded-interacting protein |
UniProt Gene Name: | RBMS1 |
UniProt Entry Name: | RBMS1_HUMAN |