PTGER1 Antibody (PACO20289)
- SKU:
- PACO20289
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PTGER1 Antibody (PACO20289) |
抗体コード: | PACO20289 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human PTGER1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20289(PTGER1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. |
シノニム: | prostaglandin E receptor 1 (subtype EP1), 42kDa |
UniProt Protein Function: | PTGER1: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 19p13.1 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:prostaglandin E receptor activity Biological Process: G-protein coupled receptor protein signaling pathway; response to lipopolysaccharide |
NCBI Summary: | The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008] |
UniProt Code: | P34995 |
NCBI GenInfo Identifier: | 83287886 |
NCBI Gene ID: | 5731 |
NCBI Accession: | P34995.3 |
UniProt Secondary Accession: | P34995,Q5U5U4, Q86UH3, Q86VB5, Q8NHB2, |
UniProt Related Accession: | P34995 |
Molecular Weight: | 402 |
NCBI Full Name: | Prostaglandin E2 receptor EP1 subtype |
NCBI Synonym Full Names: | prostaglandin E receptor 1 (subtype EP1), 42kDa |
NCBI Official Symbol: | PTGER1 |
NCBI Official Synonym Symbols: | EP1 |
NCBI Protein Information: | prostaglandin E2 receptor EP1 subtype; prostanoid EP1 receptor; PGE receptor EP1 subtype; PGE receptor, EP1 subtype; PGE2 receptor EP1 subtype; prostaglandin E receptor 1, subtype EP1; prostaglandin E receptor 1 (subtype EP1), 42kD |
UniProt Protein Name: | Prostaglandin E2 receptor EP1 subtype |
UniProt Synonym Protein Names: | Prostanoid EP1 receptor |
Protein Family: | Epidermis-specific secreted glycoprotein |
UniProt Gene Name: | PTGER1 |
UniProt Entry Name: | PE2R1_HUMAN |