PRSS1 Antibody (PACO21120)
- SKU:
- PACO21120
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PRSS1 Antibody (PACO21120) |
抗体コード: | PACO21120 |
サイズ: | 100ul(100ug) |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant protein of human PRSS1 |
憲法: | Liquid |
ストレージバッファ: | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of Liver cell lysate,using PRSS1 antibody. |
バックグラウンド: | This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor β locus on chromosome 7. |
シノニム: | TRP1; TRY1; TRY4; TRYP1 |
UniProt Protein Function: | trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; EC 3.4.21.4; Protease; Secreted Chromosomal Location of Human Ortholog: 7q34 Cellular Component: extracellular region Molecular Function:serine-type endopeptidase activity; metal ion binding Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; vitamin metabolic process; cobalamin metabolic process; digestion; proteolysis; water-soluble vitamin metabolic process Disease: Trypsinogen Deficiency; Pancreatitis, Hereditary |
NCBI Summary: | This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7. [provided by RefSeq, Jul 2008] |
UniProt Code: | P07477 |
NCBI GenInfo Identifier: | 136408 |
NCBI Gene ID: | 5644 |
NCBI Accession: | P07477.1 |
UniProt Secondary Accession: | P07477,Q5NV57, Q7M4N3, Q7M4N4, Q92955, Q9HAN4, Q9HAN5 Q9HAN6, Q9HAN7, A1A509, A6NJ71, B2R5I5, |
UniProt Related Accession: | P07477 |
Molecular Weight: | 26,558 Da |
NCBI Full Name: | Trypsin-1 |
NCBI Synonym Full Names: | protease, serine, 1 (trypsin 1) |
NCBI Official Symbol: | PRSS1 |
NCBI Official Synonym Symbols: | TRP1; TRY1; TRY4; TRYP1 |
NCBI Protein Information: | trypsin-1; beta-trypsin; trypsinogen 1; trypsinogen A; digestive zymogen; cationic trypsinogen; nonfunctional trypsin 1 |
UniProt Protein Name: | Trypsin-1 |
UniProt Synonym Protein Names: | Beta-trypsin; Cationic trypsinogen; Serine protease 1; Trypsin ICleaved into the following 2 chains:Alpha-trypsin chain 1; Alpha-trypsin chain 2 |
Protein Family: | Tripeptidyl aminopeptidase |
UniProt Gene Name: | PRSS1 |
UniProt Entry Name: | TRY1_HUMAN |
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