POU2F2 Antibody (PACO47602)
- SKU:
- PACO47602
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | POU2F2 Antibody (PACO47602) |
抗体コード: | PACO47602 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human POU domain, class 2, transcription factor 2 protein (277-389AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Hela whole cell lysate. All lanes: POU2F2 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 52, 50, 44, 63 kDa. Observed band size: 52 kDa.. | |
Immunofluorescent analysis of HepG2 cells using PACO47602 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). | |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO47602 at dilution of 1:100. |
バックグラウンド: | Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. |
シノニム: | POU domain, class 2, transcription factor 2 (Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2) (Octamer-binding protein 2) (Oct-2) (Octamer-binding transcription factor 2) (OTF-2), POU2F2, OCT2 OTF2 |
UniProt Protein Function: | Oct2: Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3'). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression. Modulates transcription transactivation by NR3C1, AR and PGR. Isoform 5 activates the U2 small nuclear RNA (snRNA) promoter. Belongs to the POU transcription factor family. Class- 2 subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: cytoplasm; nucleus Molecular Function:protein domain specific binding; sequence-specific DNA binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; immunoglobulin secretion during immune response; mature B cell differentiation; positive regulation of transcription, DNA-dependent; cell maturation; humoral immune response |
NCBI Summary: | The protein encoded by this gene is a homeobox-containing transcription factor of the POU domain family. The encoded protein binds the octamer sequence 5'-ATTTGCAT-3', a common transcription factor binding site in immunoglobulin gene promoters. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
UniProt Code: | P09086 |
NCBI GenInfo Identifier: | 123402 |
NCBI Gene ID: | 5452 |
NCBI Accession: | P09086.3 |
UniProt Secondary Accession: | P09086,Q16648, Q7M4M8, Q9BRS4, |
UniProt Related Accession: | P09086 |
Molecular Weight: | 400 |
NCBI Full Name: | POU domain, class 2, transcription factor 2 |
NCBI Synonym Full Names: | POU class 2 homeobox 2 |
NCBI Official Symbol: | POU2F2 |
NCBI Official Synonym Symbols: | OCT2; OTF2; Oct-2 |
NCBI Protein Information: | POU domain, class 2, transcription factor 2; OTF-2; homeobox protein; octamer-binding protein 2; octamer-binding transcription factor 2; lymphoid-restricted immunoglobulin octamer-binding protein NF-A2 |
UniProt Protein Name: | POU domain, class 2, transcription factor 2 |
UniProt Synonym Protein Names: | Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Octamer-binding protein 2; Oct-2; Octamer-binding transcription factor 2; OTF-2 |
Protein Family: | POU domain, class 2, transcription factor |
UniProt Gene Name: | POU2F2 |
UniProt Entry Name: | PO2F2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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