POLD3 Antibody (PACO02357)
- SKU:
- PACO02357
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | POLD3 Antibody |
抗体コード: | PACO02357 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from the C-terminal region of human DNA pol delta3. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | POLD3; KIAA0039; DNA polymerase delta subunit 3; DNA polymerase delta subunit p66 |
UniProt Protein Function: | POLD3: Required for optimal DNA polymerase delta activity. |
UniProt Protein Details: | Protein type:Nucleotide Metabolism - pyrimidine; DNA replication; Nucleotide Metabolism - purine Chromosomal Location of Human Ortholog: 11q14 Cellular Component: mitochondrion; nucleoplasm; nucleus Molecular Function:DNA-directed DNA polymerase activity; protein binding Biological Process: bypass DNA synthesis; DNA damage response, detection of DNA damage; DNA strand elongation during DNA replication; mismatch repair; nucleotide-excision repair, DNA gap filling; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 5'-to lesion; telomere maintenance; telomere maintenance via recombination; transcription-coupled nucleotide-excision repair |
NCBI Summary: | This gene encodes the 66-kDa subunit of DNA polymerase delta. DNA polymerase delta possesses both polymerase and 3' to 5' exonuclease activity and plays a critical role in DNA replication and repair. The encoded protein plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA). Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Mar 2012] |
UniProt Code: | Q15054 |
NCBI GenInfo Identifier: | 17375506 |
NCBI Gene ID: | 10714 |
NCBI Accession: | Q15054.2 |
UniProt Secondary Accession: | Q15054,Q32MZ9, Q32N00, B7ZAI6, |
UniProt Related Accession: | Q15054 |
Molecular Weight: | 39,320 Da |
NCBI Full Name: | DNA polymerase delta subunit 3 |
NCBI Synonym Full Names: | DNA polymerase delta 3, accessory subunit |
NCBI Official Symbol: | POLD3 |
NCBI Official Synonym Symbols: | P66; P68; PPP1R128 |
NCBI Protein Information: | DNA polymerase delta subunit 3 |
UniProt Protein Name: | DNA polymerase delta subunit 3 |
UniProt Synonym Protein Names: | DNA polymerase delta subunit p66 |
UniProt Gene Name: | POLD3 |
UniProt Entry Name: | DPOD3_HUMAN |