PLIN1 Antibody, HRP conjugated (PACO53835)
- SKU:
- PACO53835
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | PLIN1 Antibody, HRP conjugated (PACO53835) |
抗体コード: | PACO53835 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Perilipin-1 protein (411-496AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels. |
シノニム: | Perilipin-1 (Lipid droplet-associated protein), PLIN1, PERI PLIN |
UniProt Protein Function: | perilipin 1: an adipocyte protein of the peripilin family. A modulator of adipocyte lipid metabolism, coating lipid storage droplets to protect them from being broken down by hormone-sensitive lipase. A major cAMP-dependent protein kinase-substrate in adipocytes, also dephosphorylated by PP1. When phosphorylated, may be maximally sensitive to HSL and when unphosphorylated, may play a role in the inhibition of lipolysis. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 15q26 Cellular Component: endoplasmic reticulum; lipid particle; cytosol Molecular Function:lipid binding Biological Process: triacylglycerol catabolic process; lipid metabolic process Disease: Lipodystrophy, Familial Partial, Type 4 |
NCBI Summary: | The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] |
UniProt Code: | O60240 |
NCBI GenInfo Identifier: | 229462739 |
NCBI Gene ID: | 5346 |
NCBI Accession: | O60240.2 |
UniProt Secondary Accession: | O60240,Q8N5Y6, |
UniProt Related Accession: | O60240 |
Molecular Weight: | 55,990 Da |
NCBI Full Name: | Perilipin-1 |
NCBI Synonym Full Names: | perilipin 1 |
NCBI Official Symbol: | PLIN1 |
NCBI Official Synonym Symbols: | PERI; PLIN; FPLD4 |
NCBI Protein Information: | perilipin-1; lipid droplet-associated protein |
UniProt Protein Name: | Perilipin-1 |
UniProt Synonym Protein Names: | Lipid droplet-associated protein |
Protein Family: | Perilipin |
UniProt Gene Name: | PLIN1 |
UniProt Entry Name: | PLIN1_HUMAN |