PLEKHA1 Antibody (PACO11294)
- SKU:
- PACO11294
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PLEKHA1 Antibody (PACO11294) |
抗体コード: | PACO11294 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human PLEKHA1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1;PLEKHA1;TAPP1 ; |
UniProt Protein Function: | PLEKHA1: Binds specifically to phosphatidylinositol 3,4- diphosphate (PtdIns3,4P2), but not to other phosphoinositides. May recruit other proteins to the plasma membrane. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Lipid-binding Chromosomal Location of Human Ortholog: 10q26.13 Cellular Component: cytoplasm; nucleoplasm; plasma membrane Molecular Function:PDZ domain binding; phosphatidylinositol-3,4-bisphosphate binding; protein binding Biological Process: B cell receptor signaling pathway; establishment of protein localization; negative regulation of protein kinase B signaling cascade; phosphoinositide 3-kinase cascade; ruffle organization and biogenesis Disease: Macular Degeneration, Age-related, 1 |
NCBI Summary: | This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.[provided by RefSeq, Sep 2010] |
UniProt Code: | Q9HB21 |
NCBI GenInfo Identifier: | 48474647 |
NCBI Gene ID: | 59338 |
NCBI Accession: | Q9HB21.2 |
UniProt Secondary Accession: | Q9HB21,Q9BVK0, B3KQ55, D3DRE2, |
UniProt Related Accession: | Q9HB21 |
Molecular Weight: | 38,113 Da |
NCBI Full Name: | Pleckstrin homology domain-containing family A member 1 |
NCBI Synonym Full Names: | pleckstrin homology domain containing A1 |
NCBI Official Symbol: | PLEKHA1 |
NCBI Official Synonym Symbols: | TAPP1 |
NCBI Protein Information: | pleckstrin homology domain-containing family A member 1 |
UniProt Protein Name: | Pleckstrin homology domain-containing family A member 1 |
UniProt Synonym Protein Names: | Tandem PH domain-containing protein 1; TAPP-1 |
Protein Family: | Pleckstrin homology domain-containing family |
UniProt Gene Name: | PLEKHA1 |
UniProt Entry Name: | PKHA1_HUMAN |