PAX5 Antibody (PACO21524)
- SKU:
- PACO21524
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | PAX5 Antibody (PACO21524) |
抗体コード: | PACO21524 |
サイズ: | 100ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:1000 |
反応性: | Human, Mouse |
免疫原: | Peptide sequence around aa.6~10(N-Y-P-T-P) derived from Human Pax5. |
憲法: | Liquid |
ストレージバッファ: | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
精製方法: | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot analysis of extracts from MOLT-4 and JK cells using Pax5 Antibody. |
バックグラウンド: | May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. |
シノニム: | BSAP |
UniProt Protein Function: | May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene. |
NCBI Summary: | This gene encodes a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. Paired box transcription factors are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. This gene encodes the B-cell lineage specific activator protein that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis and so the encoded protein may also play a role in neural development and spermatogenesis. This gene is located at 9p13, which is involved in t(9;14)(p13;q32) translocations recurring in small lymphocytic lymphomas of the plasmacytoid subtype, and in derived large-cell lymphomas. This translocation brings the potent E-mu enhancer of the IgH gene into close proximity of the PAX5 promoter, suggesting that the deregulation of transcription of this gene contributes to the pathogenesis of these lymphomas. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013] |
UniProt Code: | Q02548 |
NCBI GenInfo Identifier: | 417449 |
NCBI Gene ID: | 5079 |
NCBI Accession: | Q02548.1 |
UniProt Secondary Accession: | Q02548,O75933, Q5SFM2, Q6S728, A3QVP6, A3QVP7, A3QVP8 C0KTF6, C0KTF7, C0KTF8, C0KTF9, C0KTG0, |
UniProt Related Accession: | Q02548 |
Molecular Weight: | 34,132 Da |
NCBI Full Name: | Paired box protein Pax-5 |
NCBI Synonym Full Names: | paired box 5 |
NCBI Official Symbol: | PAX5 |
NCBI Official Synonym Symbols: | ALL3; BSAP |
NCBI Protein Information: | paired box protein Pax-5 |
UniProt Protein Name: | Paired box protein Pax-5 |
UniProt Synonym Protein Names: | B-cell-specific transcription factor; BSAP |
Protein Family: | Paired box protein |
UniProt Gene Name: | PAX5 |
UniProt Entry Name: | PAX5_HUMAN |
Antibodies | ELISA Kits |
Anti-PAX5 Antibody (CAB12048) | Pax-5 Colorimetric Cell-Based ELISA Kit |
Anti-PAX5 Antibody (CAB3068) | |
PAX5 Antibody (PACO01302) | |
PAX5 Antibody (PACO02010) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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