ODC1 Antibody, HRP conjugated (PACO25746)
- SKU:
- PACO25746
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ODC1 Antibody, HRP conjugated (PACO25746) |
抗体コード: | PACO25746 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ornithine decarboxylase protein (1-461AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | L-ornithine = putrescine + CO2. Inhibited by S-nitrosylation |
シノニム: | Ornithine decarboxylase (ODC) (EC 4.1.1.17), ODC1 |
UniProt Protein Function: | ODC: the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Other Amino Acids Metabolism - glutathione; EC 4.1.1.17; Cell cycle regulation; Lyase; Amino Acid Metabolism - arginine and proline Chromosomal Location of Human Ortholog: 2p25 Cellular Component: cytoplasm; cytosol Molecular Function:ornithine decarboxylase activity; protein binding; protein homodimerization activity Biological Process: polyamine metabolic process; putrescine biosynthetic process from ornithine; regulation of amino acid metabolic process; regulation of protein catabolic process; response to virus Disease: Colorectal Cancer |
NCBI Summary: | This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013] |
UniProt Code: | P11926 |
NCBI GenInfo Identifier: | 118377 |
NCBI Gene ID: | 4953 |
NCBI Accession: | P11926.2 |
UniProt Secondary Accession: | P11926,Q53TU3, Q6LDS9, |
UniProt Related Accession: | P11926 |
Molecular Weight: | 51,148 Da |
NCBI Full Name: | Ornithine decarboxylase |
NCBI Synonym Full Names: | ornithine decarboxylase 1 |
NCBI Official Symbol: | ODC1 |
NCBI Official Synonym Symbols: | ODC |
NCBI Protein Information: | ornithine decarboxylase |
UniProt Protein Name: | Ornithine decarboxylase |
Protein Family: | Mitochondrial 2-oxodicarboxylate carrier |
UniProt Gene Name: | ODC1 |
UniProt Entry Name: | DCOR_HUMAN |