NR5A2 Antibody, Biotin conjugated (PACO49809)
- SKU:
- PACO49809
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Description
抗体名: | NR5A2 Antibody, Biotin conjugated (PACO49809) |
抗体コード: | PACO49809 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Nuclear receptor subfamily 5 group A member 2 protein (182-291AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. |
シノニム: | Nuclear receptor subfamily 5 group A member 2 (Alpha-1-fetoprotein transcription factor) (B1-binding factor) (hB1F) (CYP7A promoter-binding factor) (Hepatocytic transcription factor) (Liver receptor homolog 1) (LRH-1), NR5A2, B1F CPF FTF |
UniProt Protein Function: | NR5A2: Binds to the sequence element 5'-AACGACCGACCTTGAG-3' of the enhancer II of hepatitis B virus genes, a critical cis-element of their expression and regulation. May be responsible for the liver-specific activity of enhancer II, probably in combination with other hepatocyte transcription factors. Key regulator of cholesterol 7-alpha-hydroxylase gene (CYP7A) expression in liver. May also contribute to the regulation of pancreas-specific genes and play important roles in embryonic development. Belongs to the nuclear hormone receptor family. NR5 subfamily. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:DNA-binding; Nuclear receptor; Transcription factor Chromosomal Location of Human Ortholog: 1q32.1 Cellular Component: nucleoplasm; cytoplasm; nucleus Molecular Function:RNA polymerase II transcription factor activity, enhancer binding; protein binding; ligand-dependent nuclear receptor activity; DNA binding; zinc ion binding; sequence-specific DNA binding; phospholipid binding; steroid hormone receptor activity; transcription factor activity Biological Process: transcription initiation from RNA polymerase II promoter; positive regulation of viral genome replication; intracellular receptor-mediated signaling pathway; bile acid metabolic process; positive regulation of transcription, DNA-dependent; endocrine pancreas development; regulation of cell proliferation; cholesterol homeostasis; embryonic development; homeostatic process; regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; steroid hormone mediated signaling; gene expression |
UniProt Code: | O00482 |
NCBI GenInfo Identifier: | 7676156 |
NCBI Gene ID: | 2494 |
NCBI Accession: | O00482.2 |
UniProt Secondary Accession: | O00482,O95642, Q147U3, B4E2P3, |
UniProt Related Accession: | O00482 |
Molecular Weight: | 541 |
NCBI Full Name: | Nuclear receptor subfamily 5 group A member 2 |
NCBI Synonym Full Names: | nuclear receptor subfamily 5, group A, member 2 |
NCBI Official Symbol: | NR5A2 |
NCBI Official Synonym Symbols: | B1F; CPF; FTF; B1F2; LRH1; LRH-1; FTZ-F1; hB1F-2; FTZ-F1beta |
NCBI Protein Information: | nuclear receptor subfamily 5 group A member 2; nuclear receptor NR5A2; liver receptor homolog 1; liver receptor homolog-1; CYP7A promoter-binding factor; hepatocytic transcription factor hB1F-3; alpha-1-fetoprotein transcription factor; liver nuclear receptor homolog-1 variant 2; fetoprotein-alpha 1 (AFP) transcription factor; b1-binding factor, hepatocyte transcription factor which activates enhancer II of hepatitis B virus |
UniProt Protein Name: | Nuclear receptor subfamily 5 group A member 2 |
UniProt Synonym Protein Names: | Alpha-1-fetoprotein transcription factor; B1-binding factor; hB1F; CYP7A promoter-binding factor; Hepatocytic transcription factor; Liver receptor homolog 1; LRH-1 |
Protein Family: | Nuclear receptor subfamily |
UniProt Gene Name: | NR5A2 |
UniProt Entry Name: | NR5A2_HUMAN |