NR5A1 Antibody (PACO03763)
- SKU:
- PACO03763
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NR5A1 Antibody |
抗体コード: | PACO03763 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from human SF-1 around the non-phosphorylation site of S203. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | NR5A1; AD4BP; FTZF1; SF1; Steroidogenic factor 1; SF-1; STF-1; Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP |
UniProt Protein Function: | STF-1: a nuclear hormone receptor of the NR5 subfamily. Essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P-450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the Muellerian inhibiting substance (AMH) gene as well as the AHCH and STAR genes. |
UniProt Protein Details: | Protein type:Nuclear receptor Chromosomal Location of Human Ortholog: 9q33 Cellular Component: nucleoplasm; nucleus Molecular Function:chromatin binding; DNA binding; enzyme binding; ligand-dependent nuclear receptor activity; phospholipid binding; protein binding; RNA polymerase II transcription factor activity, enhancer binding; transcription coactivator activity Biological Process: cell-cell signaling; hormone-mediated signaling; positive regulation of transcription from RNA polymerase II promoter; primary sex determination; regulation of steroid biosynthetic process; tissue development; transcription initiation from RNA polymerase II promoter Disease: 46,xy Sex Reversal 3; Premature Ovarian Failure 7; Spermatogenic Failure 8 |
NCBI Summary: | The protein encoded by this gene is a transcriptional activator involved in sex determination. The encoded protein binds DNA as a monomer. Defects in this gene are a cause of XY sex reversal with or without adrenal failure as well as adrenocortical insufficiency without ovarian defect. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13285 |
NCBI GenInfo Identifier: | 3121738 |
NCBI Gene ID: | 2516 |
NCBI Accession: | Q13285.2 |
UniProt Secondary Accession: | Q13285,O15196, Q5T6F5, |
UniProt Related Accession: | Q13285 |
Molecular Weight: | 51,636 Da |
NCBI Full Name: | Steroidogenic factor 1 |
NCBI Synonym Full Names: | nuclear receptor subfamily 5 group A member 1 |
NCBI Official Symbol: | NR5A1 |
NCBI Official Synonym Symbols: | ELP; SF1; FTZ1; POF7; SF-1; AD4BP; FTZF1; SPGF8; SRXY3; hSF-1 |
NCBI Protein Information: | steroidogenic factor 1 |
UniProt Protein Name: | Steroidogenic factor 1 |
UniProt Synonym Protein Names: | Adrenal 4-binding protein; Fushi tarazu factor homolog 1; Nuclear receptor subfamily 5 group A member 1; Steroid hormone receptor Ad4BP |
Protein Family: | Steroidogenic factor |
UniProt Gene Name: | NR5A1 |
UniProt Entry Name: | STF1_HUMAN |