NMU Antibody (PACO44430)
- SKU:
- PACO44430
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NMU Antibody (PACO44430) |
抗体コード: | PACO44430 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Neuromedin-U protein (35-174AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO44430 at dilution of 1:100. |
バックグラウンド: | Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. |
シノニム: | Neuromedin-U [Cleaved into: Neuromedin-U-25 (NmU-25)], NMU |
UniProt Protein Function: | NMU: Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder. Belongs to the NmU family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q12 Cellular Component: extracellular region; terminal button Molecular Function:neuromedin U receptor binding; protein binding; receptor binding Biological Process: digestion; eating behavior; G-protein coupled receptor protein signaling pathway; gastric acid secretion; neuropeptide signaling pathway; photoperiodism; positive regulation of hormone secretion; positive regulation of smooth muscle contraction; positive regulation of synaptic transmission; regulation of smooth muscle contraction; sensory perception of pain; signal transduction |
NCBI Summary: | This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide. [provided by RefSeq, Jul 2015] |
UniProt Code: | P48645 |
NCBI GenInfo Identifier: | 1346685 |
NCBI Gene ID: | 10874 |
NCBI Accession: | P48645.1 |
UniProt Secondary Accession: | P48645,P12760, |
UniProt Related Accession: | P48645 |
Molecular Weight: | 19,741 Da |
NCBI Full Name: | Neuromedin-U |
NCBI Synonym Full Names: | neuromedin U |
NCBI Official Symbol: | NMU |
NCBI Protein Information: | neuromedin-U |
UniProt Protein Name: | Neuromedin-U |
Protein Family: | Neuromedin |
UniProt Gene Name: | NMU |
UniProt Entry Name: | NMU_HUMAN |
Antibodies | ELISA Kits |
Anti-NMU Antibody (CAB7068) | Human NMU / Neuromedin-U ELISA Kit |
NMU Antibody (PACO01164) | Human Neuromedin-U (NMU) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |