NLRC5 Antibody, HRP conjugated (PACO58233)
- SKU:
- PACO58233
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | NLRC5 Antibody, HRP conjugated (PACO58233) |
抗体コード: | PACO58233 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein NLRC5 protein (95-208AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. |
シノニム: | Protein NLRC5 (Caterpiller protein 16.1) (CLR16.1) (Nucleotide-binding oligomerization domain protein 27) (Nucleotide-binding oligomerization domain protein 4), NLRC5, NOD27 NOD4 |
UniProt Protein Function: | NLRC5: Probable regulator of the NF-kappa-B and type I interferon signaling pathways. May also regulate the type II interferon signaling pathway. Plays a role in homeostatic control of innate immunity and in antiviral defense mechanisms. Belongs to the NLRP family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 16q13 Cellular Component: cytoplasm; cytosol; nucleus Molecular Function:protein binding; ATP binding Biological Process: regulation of kinase activity; inhibition of NF-kappaB transcription factor; innate immune response; positive regulation of transcription from RNA polymerase II promoter; positive regulation of MHC class I biosynthetic process; defense response to virus; negative regulation of interferon type I production |
NCBI Summary: | This gene encodes a member of the caspase recruitment domain-containing NLR family. This gene plays a role in cytokine response and antiviral immunity through its inhibition of NF-kappa-B activation and negative regulation of type I interferon signaling pathways. [provided by RefSeq, Oct 2011] |
UniProt Code: | Q86WI3 |
NCBI GenInfo Identifier: | 350529351 |
NCBI Gene ID: | 84166 |
NCBI Accession: | NP_115582 |
UniProt Secondary Accession: | Q86WI3,Q6P4A6, Q86VM7, Q8NF42, Q8TEE2, Q8TEJ1, Q969L7 B5MEF1, C9JMD8, |
UniProt Related Accession: | Q86WI3 |
Molecular Weight: | 170,417 Da |
NCBI Full Name: | protein NLRC5 |
NCBI Synonym Full Names: | NLR family, CARD domain containing 5 |
NCBI Official Symbol: | NLRC5 |
NCBI Official Synonym Symbols: | NOD4; NOD27; CLR16.1 |
NCBI Protein Information: | protein NLRC5 |
UniProt Protein Name: | Protein NLRC5 |
UniProt Synonym Protein Names: | Caterpiller protein 16.1; CLR16.1; Nucleotide-binding oligomerization domain protein 27; Nucleotide-binding oligomerization domain protein 4 |
UniProt Gene Name: | NLRC5 |
UniProt Entry Name: | NLRC5_HUMAN |