NGB Antibody, HRP conjugated (PACO28559)
- SKU:
- PACO28559
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | NGB Antibody, HRP conjugated (PACO28559) |
抗体コード: | PACO28559 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Neuroglobin protein (1-151AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. |
シノニム: | Neuroglobin, NGB |
UniProt Protein Function: | NGB: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. Belongs to the globin family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q24.3 Cellular Component: mitochondrion; perikaryon Molecular Function:iron ion binding; heme binding; oxygen binding; oxygen transporter activity Biological Process: apoptosis; oxygen transport |
NCBI Summary: | This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NPG2 |
NCBI GenInfo Identifier: | 32171399 |
NCBI Gene ID: | 58157 |
NCBI Accession: | Q9NPG2.1 |
UniProt Related Accession: | Q9NPG2 |
Molecular Weight: | 151 |
NCBI Full Name: | Neuroglobin |
NCBI Synonym Full Names: | neuroglobin |
NCBI Official Symbol: | NGB |
NCBI Protein Information: | neuroglobin |
UniProt Protein Name: | Neuroglobin |
Protein Family: | Neuroglobin |
UniProt Gene Name: | NGB |
UniProt Entry Name: | NGB_HUMAN |