NFS1 Antibody (PACO10838)
- SKU:
- PACO10838
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NFS1 Antibody (PACO10838) |
抗体コード: | PACO10838 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human NFS1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | NFS1 nitrogen fixation 1 homolog (S. cerevisiae);NFS1;HUSSY-08;IscS;NIFS ; |
UniProt Protein Function: | NFS1: Catalyzes the removal of elemental sulfur from cysteine to produce alanine. It supplies the inorganic sulfur for iron- sulfur (Fe-S) clusters. May be involved in the biosynthesis of molybdenum cofactor. Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. 2 isoforms of the human protein are produced by alternative initiation. |
UniProt Protein Details: | Protein type:EC 2.8.1.7; Cofactor and Vitamin Metabolism - thiamine; Transferase; Mitochondrial Chromosomal Location of Human Ortholog: 20q11.22 Cellular Component: nucleoplasm; intracellular membrane-bound organelle; mitochondrion; mitochondrial matrix; cytoplasm; nucleolus; cytosol; nucleus Molecular Function:protein binding; protein homodimerization activity; cysteine desulfurase activity; pyridoxal phosphate binding Biological Process: iron incorporation into metallo-sulfur cluster; cysteine metabolic process; vitamin metabolic process; sulfur amino acid metabolic process; protein complex assembly; Mo-molybdopterin cofactor biosynthetic process; molybdopterin cofactor biosynthetic process; water-soluble vitamin metabolic process |
NCBI Summary: | Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2010] |
UniProt Code: | Q9Y697 |
NCBI GenInfo Identifier: | 62512153 |
NCBI Gene ID: | 9054 |
NCBI Accession: | Q9Y697.3 |
UniProt Secondary Accession: | Q9Y697,Q6P0L8, Q9NTZ5, Q9Y481, B3KMA5, B4DXK9, E1P5R8 F5GYK5, |
UniProt Related Accession: | Q9Y697 |
Molecular Weight: | 457 |
NCBI Full Name: | Cysteine desulfurase, mitochondrial |
NCBI Synonym Full Names: | NFS1 cysteine desulfurase |
NCBI Official Symbol: | NFS1 |
NCBI Official Synonym Symbols: | IscS; NIFS; HUSSY-08 |
NCBI Protein Information: | cysteine desulfurase, mitochondrial; NFS1 nitrogen fixation 1 homolog; nitrogen-fixing bacteria S-like protein; nitrogen fixation 1 (S. cerevisiae, homolog) |
UniProt Protein Name: | Cysteine desulfurase, mitochondrial |
Protein Family: | Cysteine desulfurase |
UniProt Gene Name: | NFS1 |
UniProt Entry Name: | NFS1_HUMAN |