NEUROG1 Antibody (PACO18751)
- SKU:
- PACO18751
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NEUROG1 Antibody (PACO18751) |
抗体コード: | PACO18751 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human NEUROG1 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Human liver cancer tissue, Primary antibody: PACO18751(NEUROG1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. | |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18751(NEUROG1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Neurogenin-1 is a protein that in humans is encoded by the NEUROG1 gene. Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. NEUROG1 has been shown to interact with CREB-binding protein and decapentaplegic homolog 1. |
シノニム: | Neurogenin 1 |
UniProt Protein Function: | neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis. |
UniProt Protein Details: | Protein type:Transcription factor; Cell development/differentiation; DNA-binding Chromosomal Location of Human Ortholog: 5q23-q31 Cellular Component: perikaryon; nucleus Molecular Function:protein dimerization activity; DNA binding; chromatin binding; transcription factor activity Biological Process: neuron differentiation; regulation of transcription from RNA polymerase II promoter; nervous system development; inner ear morphogenesis; cell fate commitment; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; positive regulation of exit from mitosis |
UniProt Code: | Q92886 |
NCBI GenInfo Identifier: | 37538313 |
NCBI Gene ID: | 4762 |
NCBI Accession: | Q92886.2 |
UniProt Related Accession: | Q92886 |
Molecular Weight: | |
NCBI Full Name: | Neurogenin-1 |
NCBI Synonym Full Names: | neurogenin 1 |
NCBI Official Symbol: | NEUROG1 |
NCBI Official Synonym Symbols: | AKA; ngn1; Math4C; bHLHa6; NEUROD3 |
NCBI Protein Information: | neurogenin-1 |
UniProt Protein Name: | Neurogenin-1 |
UniProt Synonym Protein Names: | Class A basic helix-loop-helix protein 6; bHLHa6; Neurogenic basic-helix-loop-helix protein; Neurogenic differentiation factor 3; NeuroD3 |
UniProt Gene Name: | NEUROG1 |
UniProt Entry Name: | NGN1_HUMAN |
Antibodies |
Anti-NEUROG1 Antibody (CAB3110) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |