NDUFS3 Antibody (PACO02925)
- SKU:
- PACO02925
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NDUFS3 Antibody |
抗体コード: | PACO02925 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | WB:1:500-1:2000 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from the Internal region of human NDUFS3. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | NDUFS3; NADH dehydrogenase [ubiquinone] iron-sulfur protein 3; mitochondrial; Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit |
UniProt Protein Function: | NDUFS3: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I 30 kDa subunit family. |
UniProt Protein Details: | Protein type:EC 1.6.5.3; Oxidoreductase; EC 1.6.99.3; Energy Metabolism - oxidative phosphorylation; Mitochondrial Chromosomal Location of Human Ortholog: 11p11.11 Cellular Component: mitochondrial matrix; mitochondrial membrane; mitochondrial respiratory chain complex I; mitochondrion; nucleus Molecular Function:NADH dehydrogenase activity; protein binding Biological Process: mitochondrial electron transport, NADH to ubiquinone; mitochondrial respiratory chain complex I assembly; negative regulation of cell growth; substantia nigra development Disease: Leigh Syndrome; Mitochondrial Complex I Deficiency |
NCBI Summary: | This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency.[provided by RefSeq, Apr 2009] |
UniProt Code: | O75489 |
NCBI GenInfo Identifier: | 6166589 |
NCBI Gene ID: | 4722 |
NCBI Accession: | O75489.1 |
UniProt Secondary Accession: | O75489,Q9UNQ8, B2R9J1, B4DFM8, |
UniProt Related Accession: | O75489 |
Molecular Weight: | 14,679 Da |
NCBI Full Name: | NADH dehydrogenase |
NCBI Synonym Full Names: | NADH:ubiquinone oxidoreductase core subunit S3 |
NCBI Official Symbol: | NDUFS3 |
NCBI Official Synonym Symbols: | CI-30 |
NCBI Protein Information: | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
UniProt Protein Name: | NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial |
UniProt Synonym Protein Names: | Complex I-30kD; CI-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit |
UniProt Gene Name: | NDUFS3 |
UniProt Entry Name: | NDUS3_HUMAN |