NASP Antibody (PACO44396)
- SKU:
- PACO44396
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NASP Antibody (PACO44396) |
抗体コード: | PACO44396 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Nuclear autoantigenic sperm protein (519-788AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO44396 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO44396 at dilution of 1:100. |
バックグラウンド: | Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA (By similarity). |
シノニム: | Nuclear autoantigenic sperm protein (NASP), NASP |
UniProt Protein Function: | NASP: Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and H1 linker histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA. Belongs to the NASP family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 1p34.1 Cellular Component: nucleoplasm; protein complex; cytoplasm; nuclear chromatin; nucleus Molecular Function:histone binding; Hsp90 protein binding Biological Process: cell proliferation; blastocyst development; protein transport; DNA replication-independent nucleosome assembly; histone exchange; cell cycle; DNA replication; DNA replication-dependent nucleosome assembly |
UniProt Code: | P49321 |
NCBI GenInfo Identifier: | 23503077 |
NCBI Gene ID: | |
NCBI Accession: | P49321.2 |
Molecular Weight: | ~ 85kDa |
NCBI Full Name: | Nuclear autoantigenic sperm protein |
UniProt Protein Name: | Nuclear autoantigenic sperm protein |
Protein Family: | NASP-related protein |
UniProt Gene Name: | NASP |
UniProt Entry Name: | NASP_HUMAN |