NAMPT Antibody (PACO10722)
- SKU:
- PACO10722
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | NAMPT Antibody (PACO10722) |
抗体コード: | PACO10722 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human NAMPT |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | nicotinamide phosphoribosyltransferase;NAMPT;1110035O14Rik;DKFZp666B131;MGC117256;PBEF;PBEF1;VF;VISFATIN ; |
UniProt Protein Function: | PBEF: an ubiquitous protein originally described as a cytokine which acts on early B-lineage precursor cells. Other reports indicate that PBEF is not a cytokine-like secreted protein but an intracellular protein associated with the cell cycle. Contains a catalytically active nicotinate phosphoribosyltransferase domain, an enzyme involved in nicotinamide adenine dinucleotide (NAD) biosynthesis. |
UniProt Protein Details: | Protein type:Cell cycle regulation; Transferase; EC 2.4.2.12; Cytokine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide Chromosomal Location of Human Ortholog: 7q22.3 Cellular Component: extracellular space; cytosol; nucleus Molecular Function:protein binding; protein homodimerization activity; cytokine activity; nicotinate-nucleotide diphosphorylase (carboxylating) activity; drug binding; nicotinamide phosphoribosyltransferase activity Biological Process: circadian rhythm; vitamin metabolic process; positive regulation of smooth muscle cell proliferation; female pregnancy; signal transduction; response to organic cyclic substance; NAD biosynthetic process; cell-cell signaling; NAD metabolic process; nicotinamide metabolic process; positive regulation of cell proliferation; insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; circadian regulation of gene expression; water-soluble vitamin metabolic process; positive regulation of nitric-oxide synthase biosynthetic process |
NCBI Summary: | This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein belongs to the nicotinic acid phosphoribosyltransferase (NAPRTase) family and is thought to be involved in many important biological processes, including metabolism, stress response and aging. This gene has a pseudogene on chromosome 10. [provided by RefSeq, Feb 2011] |
UniProt Code: | P43490 |
NCBI GenInfo Identifier: | 1172027 |
NCBI Gene ID: | 10135 |
NCBI Accession: | P43490.1 |
UniProt Related Accession: | P43490 |
Molecular Weight: | |
NCBI Full Name: | Nicotinamide phosphoribosyltransferase |
NCBI Synonym Full Names: | nicotinamide phosphoribosyltransferase |
NCBI Official Symbol: | NAMPT |
NCBI Official Synonym Symbols: | VF; PBEF; PBEF1; VISFATIN; 1110035O14Rik |
NCBI Protein Information: | nicotinamide phosphoribosyltransferase |
UniProt Protein Name: | Nicotinamide phosphoribosyltransferase |
UniProt Synonym Protein Names: | Pre-B-cell colony-enhancing factor 1; Pre-B cell-enhancing factor; Visfatin |
UniProt Gene Name: | NAMPT |
UniProt Entry Name: | NAMPT_HUMAN |