NAA60 Antibody (PACO58536)
- SKU:
- PACO58536
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | NAA60 Antibody (PACO58536) |
抗体コード: | PACO58536 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
反応性: | Human |
免疫原: | Recombinant Human N-alpha-acetyltransferase 60 protein (1-94AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO58536 diluted at 1:900 and staining in paraffin-embedded human liver cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | N-alpha-acetyltransferase that specifically mediates the acetylation of N-terminal residues of the transmembrane proteins, with a strong preference for N-termini facing the cytosol. Displays N-terminal acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. May also show histone acetyltransferase activity; such results are however unclear in vivo and would require additional experimental evidences. |
シノニム: | N-alpha-acetyltransferase 60 (hNaa60) (EC 2.3.1.259) (Histone acetyltransferase type B protein 4) (HAT4) (EC 2.3.1.48) (N-acetyltransferase 15) (N-alpha-acetyltransferase F) (NatF), NAA60, HAT4 NAT15 |
UniProt Protein Function: | NAT15: Histone acetyltransferase localized in the Golgi apparatus that mediates acetylation of free histone H4, thereby facilitating nucleosome assembly. Has a preference for free histone H4 'Lys-20'(H4K20ac), 'Lys-79'(H4K79ac) and 'Lys-91' (H4K91ac). Also displays alpha (N-terminal) acetyltransferase activity towards a range of N-terminal sequences including those starting with Met-Lys, Met-Val, Met-Ala and Met-Met. Required for normal chromosomal segregation during anaphase. Belongs to the acetyltransferase family. NAA60 subfamily. 5 isoforms of the human protein are produced by alternative promoter. |
UniProt Protein Details: | Protein type:EC 2.3.1.48; Acetyltransferase; EC 2.3.1.88 Chromosomal Location of Human Ortholog: 16p13.3 Cellular Component: Golgi membrane Molecular Function:peptide alpha-N-acetyltransferase activity; H4 histone acetyltransferase activity Biological Process: nucleosome assembly; cell proliferation; N-terminal peptidyl-methionine acetylation; chromosome segregation |
UniProt Code: | Q9H7X0 |
NCBI GenInfo Identifier: | 74733721 |
NCBI Gene ID: | 79903 |
NCBI Accession: | Q9H7X0.1 |
UniProt Secondary Accession: | Q9H7X0,Q6IA31, Q6UX26, B3KRQ0, B4DLZ0, B4DPZ8, B4DYC4 D3DUC2, E7EQ65, |
UniProt Related Accession: | Q9H7X0 |
Molecular Weight: | 242 |
NCBI Full Name: | N-alpha-acetyltransferase 60 |
NCBI Synonym Full Names: | N(alpha)-acetyltransferase 60, NatF catalytic subunit |
NCBI Official Symbol: | NAA60 |
NCBI Official Synonym Symbols: | HAT4; NAT15 |
NCBI Protein Information: | N-alpha-acetyltransferase 60; natF catalytic subunit; histone acetyltransferase type B protein 4; N-acetyltransferase 15 (GCN5-related, putative) |
UniProt Protein Name: | N-alpha-acetyltransferase 60 |
UniProt Synonym Protein Names: | Histone acetyltransferase type B protein 4; HAT4; N-acetyltransferase 15; NatF catalytic subunit |
Protein Family: | N-alpha-acetyltransferase |
UniProt Gene Name: | NAA60 |
UniProt Entry Name: | NAA60_HUMAN |
Antibodies |
Anti-NAA60 Antibody (CAB7386) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |