MVD Antibody (PACO20052)
- SKU:
- PACO20052
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MVD Antibody (PACO20052) |
抗体コード: | PACO20052 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Synthetic peptide of human MVD |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO20052(MVD Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. |
シノニム: | mevalonate (diphospho) decarboxylase |
UniProt Protein Function: | MVD: Performs the first committed step in the biosynthesis of isoprenes. Belongs to the diphosphomevalonate decarboxylase family. |
UniProt Protein Details: | Protein type:Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Lyase; EC 4.1.1.33 Chromosomal Location of Human Ortholog: 16q24.3 Cellular Component: cytosol; peroxisome Molecular Function:diphosphomevalonate decarboxylase activity; Hsp70 protein binding; protein homodimerization activity Biological Process: cholesterol biosynthetic process; dolichyl diphosphate biosynthetic process; isopentenyl diphosphate biosynthetic process, mevalonate pathway; isoprenoid biosynthetic process; positive regulation of cell proliferation |
NCBI Summary: | The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. [provided by RefSeq, Jul 2008] |
UniProt Code: | P53602 |
NCBI GenInfo Identifier: | 1706681 |
NCBI Gene ID: | 4597 |
NCBI Accession: | P53602.1 |
UniProt Secondary Accession: | P53602,Q53Y65, |
UniProt Related Accession: | P53602 |
Molecular Weight: | 43,405 Da |
NCBI Full Name: | Diphosphomevalonate decarboxylase |
NCBI Synonym Full Names: | mevalonate diphosphate decarboxylase |
NCBI Official Symbol: | MVD |
NCBI Official Synonym Symbols: | MPD; MDDase; POROK7; FP17780 |
NCBI Protein Information: | diphosphomevalonate decarboxylase |
UniProt Protein Name: | Diphosphomevalonate decarboxylase |
UniProt Synonym Protein Names: | Mevalonate (diphospho)decarboxylase; MDDase; Mevalonate pyrophosphate decarboxylase |
UniProt Gene Name: | MVD |
UniProt Entry Name: | MVD1_HUMAN |