MTHFD1L Antibody (PACO10639)
- SKU:
- PACO10639
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MTHFD1L Antibody (PACO10639) |
抗体コード: | PACO10639 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human MTHFD1L |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like;MTHFD1L;DKFZp586G1517;FLJ21145;FTHFSDC1;MTC1THFS;dJ292B18.2 ; |
UniProt Protein Function: | MTHFD1L: May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Carbohydrate Metabolism - glyoxylate and dicarboxylate; EC 6.3.4.3; Mitochondrial; Cofactor and Vitamin Metabolism - one carbon pool by folate; Ligase Chromosomal Location of Human Ortholog: 6q25.1 Cellular Component: membrane; mitochondrion; cytosol Molecular Function:methylenetetrahydrofolate dehydrogenase (NADP+) activity; protein homodimerization activity; formate-tetrahydrofolate ligase activity; methenyltetrahydrofolate cyclohydrolase activity; ATP binding Biological Process: folic acid and derivative metabolic process; tetrahydrofolate metabolic process; folic acid and derivative biosynthetic process; formate metabolic process; one-carbon compound metabolic process |
NCBI Summary: | The protein encoded by this gene is involved in the synthesis of tetrahydrofolate (THF) in the mitochondrion. THF is important in the de novo synthesis of purines and thymidylate and in the regeneration of methionine from homocysteine. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jun 2011] |
UniProt Code: | Q6UB35 |
NCBI GenInfo Identifier: | 74749360 |
NCBI Gene ID: | 25902 |
NCBI Accession: | Q6UB35.1 |
UniProt Related Accession: | Q6UB35 |
Molecular Weight: | 106kDa |
NCBI Full Name: | Monofunctional C1-tetrahydrofolate synthase, mitochondrial |
NCBI Synonym Full Names: | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like |
NCBI Official Symbol: | MTHFD1L |
NCBI Official Synonym Symbols: | FTHFSDC1; MTC1THFS; dJ292B18.2 |
NCBI Protein Information: | monofunctional C1-tetrahydrofolate synthase, mitochondrial |
UniProt Protein Name: | Monofunctional C1-tetrahydrofolate synthase, mitochondrial |
UniProt Synonym Protein Names: | Formyltetrahydrofolate synthetase |
Protein Family: | Monofunctional C1-tetrahydrofolate synthase |
UniProt Gene Name: | MTHFD1L |
UniProt Entry Name: | C1TM_HUMAN |