MTBP Antibody (PACO58436)
- SKU:
- PACO58436
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MTBP Antibody (PACO58436) |
抗体コード: | PACO58436 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
反応性: | Human |
免疫原: | Recombinant Human Mdm2-binding protein (567-724AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
IHC image of PACO58436 diluted at 1:400 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation. |
シノニム: | Mdm2-binding protein (hMTBP), MTBP |
NCBI Summary: | This gene encodes a protein that interacts with the oncoprotein mouse double minute 2. The encoded protein regulates progression through the cell cycle and may be involved in tumor formation. [provided by RefSeq, Aug 2012] |
UniProt Code: | Q96DY7 |
NCBI GenInfo Identifier: | 74731509 |
NCBI Gene ID: | 27085 |
NCBI Accession: | Q96DY7.1 |
UniProt Related Accession: | Q96DY7 |
Molecular Weight: | 36kDa |
NCBI Full Name: | |
NCBI Synonym Full Names: | MDM2 binding protein |
NCBI Official Symbol: | MTBP |
NCBI Official Synonym Symbols: | MDM2BP |
NCBI Protein Information: | mdm2-binding protein |
UniProt Protein Name: | |
Protein Family: | Mdm2-binding protein |
UniProt Gene Name: |
Antibodies | ELISA Kits |
Anti-MTBP Antibody (CAB12363) | Human MTBP / Mdm2-Binding Protein ELISA Kit |
Human Mdm2-binding protein (MTBP) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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