MSRB2 Antibody (PACO44448)
- SKU:
- PACO44448
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MSRB2 Antibody (PACO44448) |
抗体コード: | PACO44448 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Methionine-R-sulfoxide reductase B2, mitochondrial protein (10-182AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MSRB2antibody at 2.66µg/ml. Lane 1: Mouse heart tissue. Lane 2: Mouse brain tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 20 kDa. Observed band size: 20 kDa.. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO44448 at dilution of 1:100. |
バックグラウンド: | Methionine-sulfoxide reductase that specifically reduces methionine (R)-sulfoxide back to methionine. While in many cases, methionine oxidation is the result of random oxidation following oxidative stress, methionine oxidation is also a post-translational modification that takes place on specific residue. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. |
シノニム: | Methionine-R-sulfoxide reductase B2, mitochondrial (MsrB2) (EC 1.8.4.12) (EC 1.8.4.14), MSRB2, CBS-1 MSRB |
UniProt Protein Function: | MSRB2: Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Upon oxidative stress, may play a role in the preservation of mitochondrial integrity by decreasing the intracellular reactive oxygen species build-up through its scavenging role, hence contributing to cell survival and protein maintenance. Belongs to the MsrB Met sulfoxide reductase family. |
UniProt Protein Details: | Protein type:EC 1.8.4.-; Oxidoreductase; Mitochondrial; Transcription factor Chromosomal Location of Human Ortholog: 10p12 Cellular Component: mitochondrion Molecular Function:zinc ion binding; peptide-methionine (R)-S-oxide reductase activity; actin binding; transcription factor activity Biological Process: protein repair; regulation of transcription, DNA-dependent; actin filament polymerization; response to oxidative stress |
UniProt Code: | Q9Y3D2 |
NCBI GenInfo Identifier: | 182676405 |
NCBI Gene ID: | 22921 |
NCBI Accession: | Q9Y3D2.2 |
UniProt Secondary Accession: | Q9Y3D2,Q17R44, Q4G1C7, Q9Y5W6, |
UniProt Related Accession: | Q9Y3D2 |
Molecular Weight: | 19,536 Da |
NCBI Full Name: | Methionine-R-sulfoxide reductase B2, mitochondrial |
NCBI Synonym Full Names: | methionine sulfoxide reductase B2 |
NCBI Official Symbol: | MSRB2 |
NCBI Official Synonym Symbols: | CBS1; MSRB; PILB; CBS-1; CGI-131 |
NCBI Protein Information: | methionine-R-sulfoxide reductase B2, mitochondrial; pilin-like transcription factor |
UniProt Protein Name: | Methionine-R-sulfoxide reductase B2, mitochondrial |
Protein Family: | Methionine-R-sulfoxide reductase |
UniProt Gene Name: | MSRB2 |
UniProt Entry Name: | MSRB2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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