MRPS22 Antibody (PACO45096)
- SKU:
- PACO45096
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MRPS22 Antibody (PACO45096) |
抗体コード: | PACO45096 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human 28S ribosomal protein S22, mitochondrial protein (1-360AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: MRPS22 antibody at 2.36 µg/ml + Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 42, 19 kDa. Observed band size: 42 kDa.. | |
Immunohistochemistry of paraffin-embedded human lung cancer using PACO45096 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO45096 at dilution of 1:100. |
バックグラウンド: | mitochondrial inner membrane, mitochondrial ribosome, mitochondrial small ribosomal subunit, mitochondrion, structural constituent of ribosome, mitochondrial translational elongation, mitochondrial translational termination |
シノニム: | 28S ribosomal protein S22, mitochondrial (MRP-S22) (S22mt) (Mitochondrial small ribosomal subunit protein mS22), MRPS22, C3orf5 RPMS22 |
UniProt Protein Function: | MRPS22: Defects in MRPS22 are the cause of combined oxidative phosphorylation deficiency type 5 (COXPD5). COXPD5 is an antenatal mitochondrial disease. Patients show edema, cardiomyopathy, tubulopathy, and hypotonia. |
UniProt Protein Details: | Protein type:Mitochondrial; Ribosomal; Translation Chromosomal Location of Human Ortholog: 3q23 Cellular Component: mitochondrial inner membrane; mitochondrial ribosome; mitochondrial small ribosomal subunit; mitochondrion Molecular Function:structural constituent of ribosome Biological Process: mitochondrial translation; organelle organization and biogenesis Disease: Combined Oxidative Phosphorylation Deficiency 5 |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that does not seem to have a counterpart in prokaryotic and fungal-mitochondrial ribosomes. This gene lies telomeric of and is transcribed in the opposite direction from the forkhead box L2 gene. A pseudogene corresponding to this gene is found on chromosome Xq. [provided by RefSeq, Jul 2008] |
UniProt Code: | P82650 |
NCBI GenInfo Identifier: | 13633893 |
NCBI Gene ID: | 56945 |
NCBI Accession: | P82650.1 |
UniProt Secondary Accession: | P82650,Q9H3I1, |
UniProt Related Accession: | P82650 |
Molecular Weight: | 18,972 Da |
NCBI Full Name: | 28S ribosomal protein S22, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein S22 |
NCBI Official Symbol: | MRPS22 |
NCBI Official Synonym Symbols: | GIBT; GK002; C3orf5; COXPD5; RPMS22; MRP-S22 |
NCBI Protein Information: | 28S ribosomal protein S22, mitochondrial |
UniProt Protein Name: | 28S ribosomal protein S22, mitochondrial |
Protein Family: | 28S ribosomal protein |
UniProt Gene Name: | MRPS22 |
UniProt Entry Name: | RT22_HUMAN |
Antibodies |
Anti-MRPS22 Antibody (CAB12597) |
Anti-MRPS22 Antibody (CAB8319) |
MRPS22 Antibody (PACO06656) |
MRPS22 Antibody (PACO10606) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |