MGMT Antibody (PACO10483)
- SKU:
- PACO10483
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | MGMT Antibody (PACO10483) |
抗体コード: | PACO10483 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human MGMT |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | O-6-methylguanine-DNA methyltransferase; |
UniProt Protein Function: | MGMT: Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. Belongs to the MGMT family. |
UniProt Protein Details: | Protein type:EC 2.1.1.63; Methyltransferase; Nuclear receptor co-regulator; DNA repair, damage; Apoptosis Chromosomal Location of Human Ortholog: 10q26 Cellular Component: nucleoplasm; membrane; nucleus Molecular Function:methyltransferase activity; DNA binding; methylated-DNA-[protein]-cysteine S-methyltransferase activity; damaged DNA binding; calcium ion binding; DNA-methyltransferase activity Biological Process: response to drug; response to ethanol; positive regulation of DNA repair; DNA dealkylation; response to folic acid; response to toxin; DNA methylation; regulation of caspase activity; DNA repair; DNA ligation |
UniProt Code: | P16455 |
NCBI GenInfo Identifier: | 127069 |
NCBI Gene ID: | 4255 |
NCBI Accession: | P16455.1 |
UniProt Secondary Accession: | P16455,Q5VY78, |
UniProt Related Accession: | P16455 |
Molecular Weight: | 21,646 Da |
NCBI Full Name: | Methylated-DNA--protein-cysteine methyltransferase |
NCBI Synonym Full Names: | O-6-methylguanine-DNA methyltransferase |
NCBI Official Symbol: | MGMT |
NCBI Protein Information: | methylated-DNA--protein-cysteine methyltransferase; methylguanine-DNA methyltransferase; O-6-methylguanine-DNA-alkyltransferase; O6-methylguanine-DNA methyltransferase; 6-O-methylguanine-DNA methyltransferase |
UniProt Protein Name: | Methylated-DNA--protein-cysteine methyltransferase |
UniProt Synonym Protein Names: | 6-O-methylguanine-DNA methyltransferase; MGMT; O-6-methylguanine-DNA-alkyltransferase |
Protein Family: | Probable methylated-DNA--protein-cysteine methyltransferase |
UniProt Gene Name: | MGMT |
UniProt Entry Name: | MGMT_HUMAN |