LIPC Antibody (PACO02877)
- SKU:
- PACO02877
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | LIPC Antibody |
抗体コード: | PACO02877 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human |
免疫原: | synthesized peptide derived from the Internal region of human Hepatic Lipase. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | LIPC; HTGL; Hepatic triacylglycerol lipase; HL; Hepatic lipase; Lipase member C |
UniProt Protein Function: | LIPC: Hepatic lipase has the capacity to catalyze hydrolysis of phospholipids, mono-, di-, and triglycerides, and acyl-CoA thioesters. It is an important enzyme in HDL metabolism. Hepatic lipase binds heparin. Defects in LIPC are the cause of hepatic lipase deficiency (HL deficiency). A disorder characterized by elevated levels of beta-migrating very low density lipoproteins, and abnormally triglyceride-rich low and high density lipoproteins. Belongs to the AB hydrolase superfamily. Lipase family. |
UniProt Protein Details: | Protein type:Secreted; EC 3.1.1.3; Secreted, signal peptide; Lipid Metabolism - glycerolipid; Phospholipase Chromosomal Location of Human Ortholog: 15q21-q23 Cellular Component: endoplasmic reticulum lumen; extracellular region; extracellular space Molecular Function:apolipoprotein binding; low-density lipoprotein binding; phospholipase activity; triacylglycerol lipase activity Biological Process: cholesterol homeostasis; fatty acid biosynthetic process; lipid digestion; reverse cholesterol transport; triacylglycerol catabolic process Disease: Diabetes Mellitus, Noninsulin-dependent; Hepatic Lipase Deficiency; High Density Lipoprotein Cholesterol Level Quantitative Trait Locus 12 |
NCBI Summary: | LIPC encodes hepatic triglyceride lipase, which is expressed in liver. LIPC has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. [provided by RefSeq, Jul 2008] |
UniProt Code: | P11150 |
NCBI GenInfo Identifier: | 317373430 |
NCBI Gene ID: | 3990 |
NCBI Accession: | P11150.3 |
UniProt Secondary Accession: | P11150,O43571, P78529, Q99465, A2RUB4, A8K9B6, |
UniProt Related Accession: | P11150 |
Molecular Weight: | 55,914 Da |
NCBI Full Name: | Hepatic triacylglycerol lipase |
NCBI Synonym Full Names: | lipase C, hepatic type |
NCBI Official Symbol: | LIPC |
NCBI Official Synonym Symbols: | HL; HTGL; LIPH; HDLCQ12 |
NCBI Protein Information: | hepatic triacylglycerol lipase |
UniProt Protein Name: | Hepatic triacylglycerol lipase |
UniProt Synonym Protein Names: | Lipase member C |
Protein Family: | Spore germination lipase |
UniProt Gene Name: | LIPC |
UniProt Entry Name: | LIPC_HUMAN |