LIME1 Antibody, HRP conjugated (PACO61683)
- SKU:
- PACO61683
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | LIME1 Antibody, HRP conjugated (PACO61683) |
抗体コード: | PACO61683 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Lck-interacting transmembrane adapter 1 protein (170-295AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T-cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. |
シノニム: | Lck-interacting transmembrane adapter 1, Lck-interacting membrane protein, Lck-interacting molecule, LIME1, LIME, LP8067 |
UniProt Protein Function: | LIME1: Involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and TCR (T-cell antigen receptor)-mediated T- cell signaling in T-cells. In absence of TCR signaling, may be involved in CD4-mediated inhibition of T-cell activation. Couples activation of these receptors and their associated kinases with distal intracellular events such as calcium mobilization or MAPK activation through the recruitment of PLCG2, GRB2, GRAP2, and other signaling molecules. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Adaptor/scaffold Chromosomal Location of Human Ortholog: 20q13.3 Cellular Component: extracellular space |
NCBI Summary: | This gene encodes a transmembrane adaptor protein that links the T and B-cell receptor stimulation to downstream signaling pathways via its association with the Src family kinases Lck and Lyn, respectively. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015] |
UniProt Code: | Q9H400 |
NCBI GenInfo Identifier: | 74752630 |
NCBI Gene ID: | 54923 |
NCBI Accession: | Q9H400.1 |
UniProt Secondary Accession: | Q9H400,Q5JWJ2, Q6XYB3, Q9NX69, E1P5K5, E1P5K6, |
UniProt Related Accession: | Q9H400 |
Molecular Weight: | 20,841 Da |
NCBI Full Name: | Lck-interacting transmembrane adapter 1 |
NCBI Synonym Full Names: | Lck interacting transmembrane adaptor 1 |
NCBI Official Symbol: | LIME1 |
NCBI Official Synonym Symbols: | LIME; dJ583P15.4 |
NCBI Protein Information: | lck-interacting transmembrane adapter 1 |
UniProt Protein Name: | Lck-interacting transmembrane adapter 1 |
UniProt Synonym Protein Names: | Lck-interacting molecule |
Protein Family: | Lck-interacting transmembrane adapter |
UniProt Gene Name: | LIME1 |
UniProt Entry Name: | LIME1_HUMAN |