UniProt Protein Function: | LILRA1: May act as receptor for class I MHC antigens. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13.4 Cellular Component: integral to membrane; plasma membrane Molecular Function:transmembrane receptor activity; antigen binding Biological Process: regulation of immune response; cell surface receptor linked signal transduction; immune system process; defense response |
NCBI Summary: | This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013] |
UniProt Code: | O75019 |
NCBI GenInfo Identifier: | 37537902 |
NCBI Gene ID: | 11024 |
NCBI Accession: | O75019.1 |
UniProt Secondary Accession: | O75019,O75018, Q3MJA6, |
UniProt Related Accession: | O75019 |
Molecular Weight: | 31,724 Da |
NCBI Full Name: | Leukocyte immunoglobulin-like receptor subfamily A member 1 |
NCBI Synonym Full Names: | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 |
NCBI Official Symbol: | LILRA1 |
NCBI Official Synonym Symbols: | LIR6; CD85I; LIR-6 |
NCBI Protein Information: | leukocyte immunoglobulin-like receptor subfamily A member 1; CD85 antigen-like family member I; leukocyte immunoglobulin-like receptor 6 |
UniProt Protein Name: | Leukocyte immunoglobulin-like receptor subfamily A member 1 |
UniProt Synonym Protein Names: | CD85 antigen-like family member I; Leukocyte immunoglobulin-like receptor 6; LIR-6; CD_antigen: CD85i |
Protein Family: | Leukocyte immunoglobulin-like receptor subfamily |
UniProt Gene Name: | LILRA1 |
UniProt Entry Name: | LIRA1_HUMAN |