KLF15 Antibody (PACO44583)
- SKU:
- PACO44583
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | KLF15 Antibody (PACO44583) |
抗体コード: | PACO44583 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Krueppel-like factor 15 protein (1-260AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO44583 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human gastric cancer using PACO44583 at dilution of 1:100. |
バックグラウンド: | Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CTGF expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation. |
シノニム: | Krueppel-like factor 15 (Kidney-enriched krueppel-like factor), KLF15, KKLF |
UniProt Protein Function: | KLF15: Transcriptional activator. Binds to the GA element of the CLCNKA promoter. Belongs to the Sp1 C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:DNA-binding; Transcription factor; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 3q21.3 Cellular Component: nucleus Molecular Function:protein binding; metal ion binding Biological Process: cardiac muscle hypertrophy; glial cell differentiation; transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; glucose transport |
UniProt Code: | Q9UIH9 |
NCBI GenInfo Identifier: | 20138787 |
NCBI Gene ID: | 28999 |
NCBI Accession: | Q9UIH9.1 |
UniProt Related Accession: | Q9UIH9 |
Molecular Weight: | 416 |
NCBI Full Name: | Krueppel-like factor 15 |
NCBI Synonym Full Names: | Kruppel-like factor 15 |
NCBI Official Symbol: | KLF15 |
NCBI Official Synonym Symbols: | KKLF |
NCBI Protein Information: | Krueppel-like factor 15; kidney-enriched Kruppel-like factor; kidney-enriched krueppel-like factor |
UniProt Protein Name: | Krueppel-like factor 15 |
UniProt Synonym Protein Names: | Kidney-enriched krueppel-like factor |
Protein Family: | Krueppel-like factor |
UniProt Gene Name: | KLF15 |
UniProt Entry Name: | KLF15_HUMAN |